Evidence map›Paper›PMID 31248062›Full record

ReviewInternational journal of molecular sciences2019

Death-Associated Protein Kinase 1 Phosphorylation in Neuronal Cell Death and Neurodegenerative Disease.

Nami Kim, Dongmei Chen, Xiao Zhen Zhou, Tae Ho Lee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. The role of serum/glucocorticoid-regulated kinase 1 in brain function following cerebral ischemia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  10. Review
  11. International journal of molecular sciences · 2024
    Article
  12. ACS omega · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Current neuropharmacology · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nami KimDivision of Gerontology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Dongmei ChenFujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China.
Xiao Zhen ZhouDivision of Translational Therapeutics, Department of Medicine and Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. xzhou@bidmc.harvard.edu.
Tae Ho LeeFujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases, Institute for Translational Medicine, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China. leethres@hotmail.com.
Fujian Medical University · CNBeth Israel Deaconess Medical Center · USTranslational Therapeutics (United States) · US

Funding

Alzheimer's Association AARG-17-528817Natural Science Foundation of Fujian Province 2019J01297
6 · The paper itself

Abstract

Regulated neuronal cell death plays an essential role in biological processes in normal physiology, including the development of the nervous system. However, the deregulation of neuronal apoptosis by various factors leads to neurodegenerative diseases such as ischemic stroke and Alzheimer's disease (AD). Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin (Ca

Indexed as

Alzheimer DiseaseAnimalsApoptosisBiomarkersCell DeathDeath-Associated Protein KinasesHumansMultigene FamilyNeurodegenerative DiseasesNeuronsPhosphorylationStrokeStructure-Activity RelationshipBiomarkersDAPK1 protein, humanDeath-Associated Protein KinasesAlzheimer’s disease (AD)death-associated protein kinase 1 (DAPK1)ischemic strokeneuronal cell deathphosphorylation

Identifiers

PMID31248062
PMCPMC6651373
OpenAlexW2955080130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.