ArticleInternational journal of molecular sciences2019
Differences in Mutational Profile between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma Identified Using Next Generation Sequencing.
Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Proteomic analysis reveals modulation of key proteins in follicular thyroid cancer progression.Chinese medical journal · 2026Article
- A practical ultrasound-based risk stratification system for differentiating follicular thyroid carcinoma and adenoma.Gland surgery · 2025Article
- Proteomics analysis reveals elevated RAB21 in serum-derived extracellular vesicles from patients with follicular thyroid carcinoma.Oncology letters · 2025Article
- Routine Blood Tests as Predictive Tools for Differentiating Follicular Thyroid Carcinoma From Follicular Adenoma.International journal of general medicine · 2025Article
- Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment.Journal of endocrinological investigation · 2024Article
- Diagnostic significance of ultrasound characteristics in discriminating follicular thyroid carcinoma from adenoma.BMC medical imaging · 2024Article
- Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.Heliyon · 2024Article
- Metastatic follicular thyroid cancer with a longstanding responsiveness to gemcitabine plus oxaliplatin.European thyroid journal · 2023Article
- Article
- Spatially resolved immune microenvironmental profiling for follicular thyroid carcinoma with minimal capsular invasion.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2022Article
- Diagnostic performance of next-generation sequencing and genetic profiling in thyroid nodules from a single center in China.European thyroid journal · 2022Article
- The utility of serum anti-thyroglobulin antibody and thyroglobulin in the preoperative differential diagnosis of thyroid follicular neoplasms.Endocrine · 2022Article
- Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8.The Journal of clinical endocrinology and metabolism · 2021Article
- DNA Methylation Haplotype Block Markers Efficiently Discriminate Follicular Thyroid Carcinoma from Follicular Adenoma.The Journal of clinical endocrinology and metabolism · 2021Article
- Sonographic Features Differentiating Follicular Thyroid Cancer from Follicular Adenoma-A Meta-Analysis.Cancers · 2021Article
- Papillary Thyroid Carcinoma Landscape and Its Immunological Link With Hashimoto Thyroiditis at Single-Cell Resolution.Frontiers in cell and developmental biology · 2021Article
- Malignant struma ovarii: next-generation sequencing of six cases revealed Nras, Braf, and Jak3 mutations.Endocrine · 2021Article
- Genetic differences in follicular thyroid carcinoma between Asian and Western countries: a systematic review.Gland surgery · 2020Review
- Loss of Integrase Interactor 1 (INI1) Expression in a Subset of Differentiated Thyroid Cancer.Diagnostics (Basel, Switzerland) · 2020Article
- Amplicon-Based NGS Panels for Actionable Cancer Target Identification in Follicular Cell-Derived Thyroid Neoplasia.Frontiers in endocrinology · 2020Article
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11 authors.
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Abstract
We aimed to identify differences in mutational status between follicular thyroid adenoma (FTA) and follicular thyroid cancer (FTC). The study included 35 patients with FTA and 35 with FTC. DNA was extracted from formalin-fixed paraffin-embedded (FFPE) samples from thyroidectomy. Next-generation sequencing (NGS) was performed with the 50-gene Ion AmpliSeq Cancer Hotspot Panel v2. Potentially pathogenic mutations were found in 14 (40%) FTA and 24 (69%) FTC patients (OR (95%CI) = 3.27 (1.22-8.75)). The number of mutations was higher in patients with FTC than FTA (
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