Evidence map›Paper›PMID 31247992›Full record

ReviewMolecules (Basel, Switzerland)2019

Enzymes for Detoxification of Various Mycotoxins: Origins and Mechanisms of Catalytic Action.

Ilya Lyagin, Elena Efremenko

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Mycotoxin Removal and Transcriptional Response ofFoods (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Aflatoxin BScientific reports · 2025
    Article
  13. Review
  14. Inhibitor of Chromosome Segregation inACS chemical biology · 2024
    Article
  15. Mitigation of Mycotoxins in Food-Is It Possible?Foods (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Article
  18. Bioenzymatic detoxification of mycotoxins.Frontiers in microbiology · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ilya LyaginFaculty of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia.ORCID 0000-0002-3970-4334
Elena EfremenkoFaculty of Chemistry, Lomonosov Moscow State University, Moscow 119991, Russia. elena_efremenko@list.ru.ORCID 0000-0002-6992-854X

Funding

Russian Science Foundation 16-14-00061
6 · The paper itself

Abstract

Mycotoxins are highly dangerous natural compounds produced by various fungi. Enzymatic transformation seems to be the most promising method for detoxification of mycotoxins. This review summarizes current information on enzymes of different classes to convert various mycotoxins. An in-depth analysis of 11 key enzyme mechanisms towards dozens of major mycotoxins was realized. Additionally, molecular docking of mycotoxins to enzymes' active centers was carried out to clarify some of these catalytic mechanisms. Analyzing protein homologues from various organisms (plants, animals, fungi, and bacteria), the prevalence and availability of natural sources of active biocatalysts with a high practical potential is discussed. The importance of multifunctional enzyme combinations for detoxification of mycotoxins is posed.

Indexed as

Inactivation, MetabolicCatalysisModels, MolecularMolecular ConformationMolecular StructureMycotoxinsPhylogenyStructure-Activity RelationshipMycotoxinsantidotebiochemical mechanismconversiondetoxificationenzymemolecular modelingmycotoxinorigins

Identifiers

PMID31247992
PMCPMC6651818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.