Evidence map›Paper›PMID 31247969›Full record

ArticleInternational journal of molecular sciences2019

Whole Body Vibration-Induced Omental Macrophage Polarization and Fecal Microbiome Modification in a Murine Model.

Jack C Yu, Vanessa L Hale, Hesam Khodadadi, Babak Baban

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jack C YuChildren's Hospital of Georgia, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. jyu@augusta.edu.
Vanessa L HaleDepartment of Oral Biology, College of Dental Medicine, Augusta University, Augusta, GA 30912, USA.
Hesam KhodadadiVeterinary Preventive Medicine, Ohio State University, College of Veterinary Medicine, Columbus, OH 43210, USA.
Babak BabanVeterinary Preventive Medicine, Ohio State University, College of Veterinary Medicine, Columbus, OH 43210, USA. bbaban@augusta.edu.
Augusta University · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human nutrient metabolism, developed millions of years ago, is anachronistic. Adaptive features that offered survival advantages are now great liabilities. The current dietary pattern, coupled with massively reduced physical activities, causes an epidemic of obesity and chronic metabolic diseases, such as type 2 diabetes mellitus. Chronic inflammation is a major contributing factor to the initiation and progression of most metabolic and cardiovascular diseases. Among all components of an innate immune system, due to their dual roles as phagocytic as well as antigen-presenting cells, macrophages play an important role in the regulation of inflammatory responses, affecting the body's microenvironment and homeostasis. Earlier studies have established the beneficial, anti-inflammatory effects of whole body vibration (WBV) as a partial exercise mimetic, including reversing the effects of glucose intolerance and hepatic steatosis. Here for the first time, we describe potential mechanisms by which WBV may improve metabolic status and ameliorate the adverse consequences through macrophage polarization and altering the fecal microbiome.

Indexed as

Gastrointestinal MicrobiomeVibrationAnimalsBiodiversityBiomarkersDiabetes Mellitus, Type 2Disease Models, AnimalFecesImmunophenotypingMacrophage ActivationMacrophagesMetagenomeMetagenomicsMiceOmentumBiomarkersinnate immunitymacrophagemicrobiomeobesitytype II diabetesWBVwhole body vibration

Identifiers

PMID31247969
PMCPMC6651746
OpenAlexW2954186776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.