Evidence map›Paper›PMID 31247880›Full record

ArticleInorganic chemistry2019

Mechanistic Insights into the Metal-Dependent Activation of Zn

Matthew R Jordan, Jiefei Wang, Andy Weiss, Eric P Skaar, Daiana A Capdevila, David P Giedroc

Open access · greenAbstract read
In one paragraph

Article in Inorganic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Microbiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. The interplay betweenInfection and immunity · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Zinc homeostasis in Pseudomonas.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Protein metalation in biology.Current opinion in chemical biology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Matthew R Jordan
Jiefei Wang
Andy WeissDepartment of Pathology, Microbiology, and Immunology , Vanderbilt University Medical Center , Nashville , Tennessee 37232 , United States.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology , Vanderbilt University Medical Center , Nashville , Tennessee 37232 , United States.
Indiana University Bloomington · USVanderbilt University Medical Center · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Host-mediated zinc sequestration during Acinetobacter baumannii infectionR01AI101171 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WALTER J. CHAZIN, DAVID P. GIEDROC · 2013 to 2026
$8.2M
MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
Transition Metal Homeostasis and Reactive Sulfur Species in Bacterial PathogensR35GM118157 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI DAVID P. GIEDROC · 2016 to 2026
$5.9M
Graduate Program in Quantitative and Chemical Biology at Indiana University BloomT32GM109825 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GIEDROC, DAVID P. · 2014 to 2018
$926k
NIAID NIH HHS R01 AI101171NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R35 GM118157NIGMS NIH HHS T32 GM008320NIGMS NIH HHS T32 GM109825
6 · The paper itself

Abstract

Members of the COG0523 subfamily of candidate GTPase metallochaperones function in bacterial transition-metal homeostasis, but the nature of the cognate metal, mechanism of metal transfer, and identification of target protein(s) for metal delivery remain open questions. Here, we explore the multifunctionality of members of the subfamily linked to delivering Zn

Indexed as

Binding SitesMetallochaperonesStaphylococcus aureusZincMetallochaperonesZinc

Identifiers

PMID31247880
PMCPMC7005846
OpenAlexW2952701327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.