Evidence map›Paper›PMID 31247718›Full record

ArticleAnalytical chemistry2019

Dendrimer-Based Platform for Effective Capture of Tumor Cells after TGFβ

Ja Hye Myung, Ashley Cha, Kevin A Tam, Michael Poellmann, Alain Borgeat, Roohollah Sharifi, Robert E Molokie, Gina Votta-Velis, Seungpyo Hong

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Towards liquid biopsy-based analysis of antitumour immunity.Nature reviews. Clinical oncology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Branched, dendritic, and hyperbranched polymers in liquid biopsy device design.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Ja Hye MyungPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin , Madison , Wisconsin 53705 , United States.
Ashley Cha
Kevin A Tam
Michael PoellmannPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin , Madison , Wisconsin 53705 , United States.ORCID 0000-0002-0085-3957
Alain BorgeatDepartment of Anesthesiology , Orthopedic University Hospital Balgrist , Zurich , Switzerland 8008.
Roohollah SharifiSection of Urology , Jessie Brown Veterans Administration Medical Center , Chicago , Illinois 60612 , United States.
Robert E Molokie
Gina Votta-VelisSection of Urology , Jessie Brown Veterans Administration Medical Center , Chicago , Illinois 60612 , United States.
Seungpyo HongPharmaceutical Sciences Division, School of Pharmacy , University of Wisconsin , Madison , Wisconsin 53705 , United States.ORCID 0000-0001-9870-031X
University of Illinois Chicago · USUniversity of Wisconsin–Madison · USUniversitätsklinik Balgrist · CH

Funding

Project 4: Role of Receptor Tyrosine Kinase AXL in HNSCC Therapy ResistanceP50DE026787 · NIDCR · UNIVERSITY OF WISCONSIN-MADISON · PI HARARI, PAUL M · 2016 to 2020
$10.8M
Potential therapeutic implications of targeting miR-150 in acute myeloid leukemiaR01CA182528 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2014 to 2018
$1.7M
CapioCyte circulating tumor cell assay as a biomarker for cancer immunotherapy responseR43CA232924 · NCI · CAPIO BIOSCIENCES, INC. · PI MILLER, STEVEN · 2018 to 2019
$212k
NCI NIH HHS R01 CA182528NCI NIH HHS R43 CA232924NIDCR NIH HHS P50 DE026787
6 · The paper itself

Abstract

Detection of circulating tumor cells (CTCs) relying on their expression of epithelial cell markers, such as epithelial cell adhesion molecule (EpCAM), has been commonly used. However, this approach unlikely captures CTCs that have undergone the process of epithelial-mesenchymal transition (EMT). In this study, we have induced EMT of in vitro prostate (PCa) and breast cancer (BCa) cell lines by treatment of transforming growth factor β 1 (TGFβ

Indexed as

Epithelial-Mesenchymal TransitionBreast NeoplasmsCell ProliferationCell SeparationDendrimersEpithelial Cell Adhesion MoleculeFemaleHumansMaleNeoplastic Cells, CirculatingPilot ProjectsProstatic NeoplasmsTransforming Growth Factor beta1Tumor Cells, CulturedDendrimersEPCAM protein, humanEpithelial Cell Adhesion MoleculeTGFB1 protein, humanTransforming Growth Factor beta1

Identifiers

PMID31247718
PMCPMC7068806
OpenAlexW2948797310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.