ArticleThe Journal of allergy and clinical immunology2019
Ambient air pollution, asthma drug response, and telomere length in African American youth.
Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Leukocyte telomere length and obesity in children and adolescents: A systematic review and meta-analysis.Frontiers in genetics · 2022Pooled it
- Telomere-associated non-malignant pulmonary diseases: Pathogenic mechanisms and therapeutic strategies.Acta pharmaceutica Sinica. B · 2026Review
- Health disparities in neurology.Nature reviews. Neurology · 2025Review
- Inhalation of concentrated ambient PM2.5 promotes inactivation of telomerase reverse transcriptase, telomere shortening, and senescence of multiple cell types in mice.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Ambient air pollution, genetic risk and telomere length in UK biobank.Journal of exposure science & environmental epidemiology · 2024Article
- The interaction of socioeconomic stress and race on telomere length in children: A systematic review and meta-analysis.SSM - population health · 2023Article
- Telomere dysfunction in some pediatric congenital and growth-related diseases.Frontiers in pediatrics · 2023Review
- Hippocampal volume indexes neurobiological sensitivity to the effect of pollution burden on telomere length in adolescents.New directions for child and adolescent development · 2022Article
- S3 guideline Allergy Prevention.Allergologie select · 2022Article
- Airway hyperresponsiveness development and the toxicity of PM2.5.Environmental science and pollution research international · 2021Review
- DNA Methylation-Based Age Prediction and Telomere Length Reveal an Accelerated Aging in Induced Sputum Cells Compared to Blood Leukocytes: A Pilot Study in COPD Patients.Frontiers in medicine · 2021Article
- Long-term ozone exposure is positively associated with telomere length in critically ill patients.Environment international · 2020Observational
- Potential Role of Cellular Senescence in Asthma.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundTelomere length (TL) can serve as a potential biomarker for conditions associated with chronic oxidative stress and inflammation, such as asthma. Air pollution can induce oxidative stress. Understanding the relationship between TL, asthma, and air pollution is important for identifying risk factors contributing to unhealthy aging in children.
objectivesWe sought to investigate associations between exposures to ambient air pollutants and TL in African American children and adolescents and to examine whether African ancestry, asthma status, and steroid medication use alter the association.
methodsLinear regression was used to examine associations between absolute telomere length (aTL) and estimated annual average residential ozone (O
resultsParticipants' aTLs were measured by using quantitative PCR. A 1-ppb and 1 μg/m
conclusionExposure to air pollution was associated with shorter TLs in nonasthmatic children and adolescents. This was not the case for asthmatic children as a group, but those receiving steroid medication had less shortening than those not using steroids. Reduced exposure to air pollution in childhood might help to preserve TL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.