Evidence map›Paper›PMID 31247027›Full record

ArticlePLoS pathogens2019

Blood brain barrier disruption in cerebral malaria: Beyond endothelial cell activation.

Arnulfo Tunon-Ortiz, Tracey J Lamb

Abstract read
In one paragraph

Article in PLoS pathogens, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Pathology of Severe Malaria.Pathogens (Basel, Switzerland) · 2023
    Article
  8. Article
  9. 3D In Vitro Blood-Brain-Barrier Model for Investigating Barrier Insults.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  10. Article
  11. Diagnosis of cerebral malaria: Tools to reduceFrontiers in cellular and infection microbiology · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arnulfo Tunon-OrtizDepartment of Pathology, University of Utah, Salt Lake City, Utah, United States of America.
Tracey J LambDepartment of Pathology, University of Utah, Salt Lake City, Utah, United States of America.ORCID 0000-0003-0620-3944

Funding

EphA2 mediates opening of the blood brain barrier in cerebral malariaR01NS097819 · NINDS · UNIVERSITY OF UTAH · PI LAMB, TRACEY JANE · 2017 to 2021
$1.8M
Ephrin ligands as novel targets for an adjunct therapy in cerebral malariaR21NS085382 · NINDS · EMORY UNIVERSITY · PI LAMB, TRACEY JANE · 2014 to 2015
$437k
NINDS NIH HHS R01 NS097819NINDS NIH HHS R21 NS085382
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBlood-Brain BarrierEndothelial CellsHumansMalaria, CerebralMalaria, FalciparumPlasmodium falciparum

Identifiers

PMID31247027
PMCPMC6597102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.