Evidence map›Paper›PMID 31246862›Full record

SynthesisJBJS reviews2019

Size and Shape of the Human Anterior Cruciate Ligament and the Impact of Sex and Skeletal Growth: A Systematic Review.

Stephanie G Cone, Danielle Howe, Matthew B Fisher

Abstract readSystematic Review
In one paragraph

Synthesis in JBJS reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Effect of Age on the Biomechanical Properties of Porcine LCL.Bioengineering (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  19. Age- and sex-specific differences in ACL and ACL bundle size during adolescent growth.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephanie G ConeJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, North Carolina.ORCID 0000-0003-0544-448
Danielle HoweJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, North Carolina.ORCID 0000-0003-1596-9060
Matthew B FisherJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, North Carolina.ORCID 0000-0002-3212-0870

Funding

Sex- and Age-dependent ACL Function in the Growing Knee JointR01AR071985 · NIAMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Matthew B Fisher · 2018 to 2026
$3.6M
Age-Dependent ACL Function During Growth: Guiding Injury Treatment in ChildrenR03AR068112 · NIAMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI FISHER, MATTHEW B · 2015 to 2017
$227k
NIAMS NIH HHS R01 AR071985NIAMS NIH HHS R03 AR068112
6 · The paper itself

Abstract

backgroundHigh rates of anterior cruciate ligament (ACL) injury and surgical reconstruction in both skeletally immature and mature populations have led to many studies investigating the size and shape of the healthy ligament. The purposes of the present study were to compile existing quantitative measurements of the geometry of the ACL, its bundles, and its insertion sites and to describe effects of common covariates such as sex and age.

methodsA search of the Web of Science was conducted for studies published from January 1, 1900, to April 11, 2018, describing length, cross-sectional area, volume, orientation, and insertion sites of the ACL. Two reviewers independently screened and reviewed the articles to collect quantitative data for each parameter.

resultsQuantitative data were collected from 92 articles in this systematic review. In studies of adults, reports of average ACL length, cross-sectional area, and volume ranged from 26 to 38 mm, 30 to 53 mm, and 854 to 1,858 mm, respectively. Reported values were commonly found to vary according to sex and skeletal maturity as well as measurement technique.

conclusionsAlthough the geometry of the ACL has been described widely in the literature, quantitative measurements can depend on sex, age, and measurement modality, contributing to variability between studies. As such, care must be taken to account for these factors. The present study condenses measurements describing the geometry of the ACL, its individual bundles, and its insertion sites, accounting for common covariates when possible, to provide a resource to the clinical and scientific communities. CLINICAL RELEVANCE: Quantitative measures of ACL geometry are informative for developing clinical treatments such as ACL reconstruction. Age and sex can impact these parameters.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionBone DevelopmentDecision Support TechniquesEvidence-Based MedicineGraft SurvivalHumansQualitative ResearchSex Factors

Identifiers

PMID31246862
PMCPMC7771555

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.