Evidence map›Paper›PMID 31246421›Full record

ArticleBiochemistry2019

Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical

James D Gumkowski, Ryan J Martinie, Patrick S Corrigan, Juan Pan, Matthew R Bauerle, Mohamed Almarei, Squire J Booker, Alexey Silakov, Carsten Krebs, Amie K Boal

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

James D GumkowskiDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0001-5791-8419
Ryan J MartinieDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0003-1257-2850
Patrick S CorriganDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
Juan PanDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0003-3307-958X
Matthew R BauerleDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
Mohamed AlmareiDepartment of Biochemistry and Molecular Biology , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
Squire J BookerDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0002-7211-5937
Alexey SilakovDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0002-9285-1253
Carsten KrebsDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0002-3302-7053
Amie K BoalDepartment of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.ORCID 0000-0002-1234-8472
Pennsylvania State University · US

Funding

Mapping the Structural Basis for Mechanistic Diversity in Metalloenzyme SuperfamiliesR35GM119707 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Amie K Boal · 2016 to 2026
$5.0M
Radical Mechanisms of Iron-Sulfur ProteinsR35GM122595 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI SQUIRE J. BOOKER · 2017 to 2026
$3.4M
Structure determination of reaction intermediates in macromolecular complexesR00GM100011 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BOAL, AMIE K · 2013 to 2015
$729k
NIGMS NIH HHS R00 GM100011NIGMS NIH HHS R35 GM119707NIGMS NIH HHS R35 GM122595
6 · The paper itself

Abstract

Cfr is a radical

Indexed as

PhylogenyAmino Acid SequenceClostridioides difficileIronMethylationProtein BindingRNAS-AdenosylmethionineIronRNAS-Adenosylmethionine

Identifiers

PMID31246421
PMCPMC6800567
OpenAlexW2955780758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.