Evidence map›Paper›PMID 31246409›Full record

ArticleACS chemical neuroscience2019

Extended (10-Day) Real-Time Monitoring by Dexamethasone-Enhanced Microdialysis in the Injured Rat Cortex.

Elaine M Robbins, Andrea Jaquins-Gerstl, David F Fine, Chi Leng Leong, C Edward Dixon, Amy K Wagner, Martyn G Boutelle, Adrian C Michael

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Real-time in vivo thoracic spinal glutamate sensing during myocardial ischemia.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Dexamethasone-Enhanced Microdialysis and Penetration Injury.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Elaine M RobbinsDepartment of Chemistry , University of Pittsburgh , Pittsburgh , Pennsylvania 15260 , United States.
Andrea Jaquins-GerstlDepartment of Chemistry , University of Pittsburgh , Pittsburgh , Pennsylvania 15260 , United States.
David F FineDepartment of Physical Medicine and Rehabilitation , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania 15213 , United States.
Chi Leng LeongDepartment of Bioengineering , Imperial College London , London SW7 2AZ , United Kingdom.
C Edward DixonDepartment of Neurological Surgery , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania 15213 , United States.
Amy K WagnerDepartment of Physical Medicine and Rehabilitation , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania 15213 , United States.
Martyn G BoutelleDepartment of Bioengineering , Imperial College London , London SW7 2AZ , United Kingdom.ORCID 0000-0003-1332-3442
Adrian C MichaelDepartment of Chemistry , University of Pittsburgh , Pittsburgh , Pennsylvania 15260 , United States.ORCID 0000-0001-9069-4664
University of Pittsburgh · USImperial College London · GB

Funding

Enhanced Bedside Microdialysis for TBIR01NS102725 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHAEL, ADRIAN C, PUCCIO, AVA M. · 2018 to 2022
$2.7M
Request for Zeiss 710 multiphoton 5Live Duoscan MicroscopeS10RR028478 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2011 to 2011
$1.1M
Enhanced Microdialysis for CSD MonitoringR21NS092245 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHAEL, ADRIAN C · 2015 to 2016
$402k
Technical enhancements for intracranial microdialysisR21NS109875 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHAEL, ADRIAN C · 2018 to 2019
$401k
NCRR NIH HHS S10 RR028478NINDS NIH HHS R01 NS102725NINDS NIH HHS R21 NS092245NINDS NIH HHS R21 NS109875
6 · The paper itself

Abstract

Intracerebral microdialysis has proven useful for chemical monitoring in patients following traumatic brain injury. Recent studies in animals, however, have documented that insertion of microdialysis probes into brain tissues initiates a foreign-body response. Within a few days after probe insertion, the foreign body response impedes the use of microdialysis to monitor the K

Indexed as

AnimalsAnti-Inflammatory AgentsBrainBrain InjuriesDexamethasoneForeign-Body ReactionGlucoseMaleMicrodialysisMonitoring, PhysiologicPotassiumRatsRats, Sprague-DawleyAnti-Inflammatory AgentsDexamethasoneGlucosePotassiumbiosensorcontrolled cortical impactdexamethasoneMicrodialysismicrofluidicspreading depolarization

Identifiers

PMID31246409
PMCPMC7341684
OpenAlexW2951627550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.