ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2020
Different Combinations of Mobility Metrics Derived From a Wearable Sensor Are Associated With Distinct Health Outcomes in Older Adults.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Early detection of diseases causing dementia using digital navigation and gait measures: A systematic review of evidence.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Functional parameters indicative of mild cognitive impairment: a systematic review using instrumented kinematic assessment.BMC geriatrics · 2020Pooled it
- Digital Predictors of Morbidity, Hospitalization, and Mortality Among Older Adults: A Systematic Review and Meta-Analysis.Frontiers in digital health · 2020Pooled it
- Turning versus straight walking under dual-task conditions: a preliminary study for identifying mild cognitive impairment and Alzheimer's disease.BMC neurology · 2026Article
- Clinical translation of fluid, imaging, and digital biomarkers for Alzheimer's disease.Alzheimer's research & therapy · 2026Review
- Multimodal passive smartphone sensing in older adults: a guide for clinical scientists based upon an ongoing cohort study.Innovation in aging · 2026Article
- Wearable Sensor Technologies and Gait Analysis for Early Detection of Dementia: Trends and Future Directions.Sensors (Basel, Switzerland) · 2025Review
- How do people with COPD walk? A European study on digitally measured real-world gait.The European respiratory journal · 2025Article
- Combining 24-Hour Continuous Monitoring of Time-Locked Heart Rate, Physical Activity and Gait in Older Adults: Preliminary Findings.Sensors (Basel, Switzerland) · 2025Article
- Machine Learning and Statistical Analyses of Sensor Data Reveal Variability Between Repeated Trials in Parkinson's Disease Mobility Assessments.Sensors (Basel, Switzerland) · 2024Article
- Mobility Abilities Mediate the Association of a More Active Lifestyle With Mobility Disability in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Remote Digital Technologies for the Early Detection and Monitoring of Cognitive Decline in Patients With Type 2 Diabetes: Insights From Studies of Neurodegenerative Diseases.Journal of diabetes science and technology · 2024Review
- Self-supervised learning of wrist-worn daily living accelerometer data improves the automated detection of gait in older adults.Scientific reports · 2024Article
- Motor and Nonmotor Measures and Declining Daily Physical Activity in Older Adults.JAMA network open · 2024Article
- Simplification of Mobility Tests and Data Processing to Increase Applicability of Wearable Sensors as Diagnostic Tools for Parkinson's Disease.Sensors (Basel, Switzerland) · 2024Article
- Automated Gait Detection in Older Adults during Daily-Living using Self-Supervised Learning of Wrist-Worn Accelerometer Data: Development and Validation of ElderNet.Research square · 2024Article
- Smartphone-based inertial measurements during Chester step test as a predictor of length of hospital stay in abdominopelvic cancer postoperative period: a prospective cohort study.World journal of surgical oncology · 2024Observational
- Shifting From Active to Passive Monitoring of Alzheimer Disease: The State of the Research.Journal of the American Heart Association · 2024Review
- Relation of Motor Impairments to Neuropathologic Changes of Limbic-Predominant Age-Related TDP-43 Encephalopathy in Older Adults.Neurology · 2023Article
- Accelerometry applications and methods to assess standing balance in older adults and mobility-limited patient populations: a narrative review.Aging clinical and experimental research · 2023Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundGait speed is a robust nonspecific predictor of health outcomes. We examined if combinations of gait speed and other mobility metrics are associated with specific health outcomes.
methodsA sensor (triaxial accelerometer and gyroscope) placed on the lower back, measured mobility in the homes of 1,249 older adults (77% female; 80.0, SD = 7.72 years). Twelve gait scores were extracted from five performances, including (a) walking, (b) transition from sit to stand, (c) transition from stand to sit, (d) turning, and (e) standing posture. Using separate Cox proportional hazards models, we examined which metrics were associated with time to mortality, incident activities of daily living disability, mobility disability, mild cognitive impairment, and Alzheimer's disease dementia. We used a single integrated analytic framework to determine which gait scores survived to predict each outcome.
resultsDuring 3.6 years of follow-up, 10 of the 12 gait scores predicted one or more of the five health outcomes. In further analyses, different combinations of 2-3 gait scores survived backward elimination and were associated with the five outcomes. Sway was one of the three scores that predicted activities of daily living disability but was not included in the final models for other outcomes. Gait speed was included along with other metrics in the final models predicting mortality and activities of daily living disability but not for other outcomes.
conclusionsWhen analyzing multiple mobility metrics together, different combinations of mobility metrics are related to specific adverse health outcomes. Digital technology enhances our understanding of impaired mobility and may provide mobility biomarkers that predict distinct health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.