Evidence map›Paper›PMID 31245968›Full record

ArticleTurkish journal of ophthalmology2019

Topographic Evaluation of Unilateral Keratoconus Patients

Cumali Değirmenci, Melis Palamar, Nergis İsmayilova, Sait Eğrilmez, Ayşe Yağcı

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Turkish journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Benefits of using corneal topography to choose subjective refraction technique in keratoconus (RE-CON): a prospective comparative crossover clinical study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  7. Current Developments in Corneal Topography and Tomography.Diagnostics (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cumali DeğirmenciEge University Faculty of Medicine, Department of Ophthalmology, İzmir, TurkeyORCID 0000-0002-8268-536X
Melis PalamarEge University Faculty of Medicine, Department of Ophthalmology, İzmir, TurkeyORCID 0000-0002-2494-0131
Nergis İsmayilovaDünyagöz Hospital, Ophthalmology Clinic, Baku, Azerbaijan
Sait EğrilmezEge University Faculty of Medicine, Department of Ophthalmology, İzmir, TurkeyORCID 0000-0002-6971-527X
Ayşe YağcıEge University Faculty of Medicine, Department of Ophthalmology, İzmir, TurkeyORCID 0000-0002-4713-2831
Ege University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To compare data obtained by Scheimpflug camera (Pentacam) from both eyes of unilateral keratoconus patients and normal controls. Materials and Methods: This study was performed by retrospective chart review of 919 keratoconus patients. From these patients, 31 keratoconus eyes of 31 patients with unilateral keratoconus (Group 1), 31 normal fellow eyes of these patients (Group 2), and 30 right eyes of 30 normal controls (Group 3) were included in the study. Detailed ophthalmologic examination and Pentacam parameters at initial examination were analyzed and relationships between Groups 1, 2, and 3 were statistically evaluated. ROC curve analysis was also performed to determine the sensitivity and specificity of parameters that could be used to differentiate Group 2 from Groups 1 and 3. Results: The mean age was 30.07±11.00 (15-60) in Group 1-2 patients and 32.33±9.30 (18-45) in Group 3 patients (p=0.392). In comparison of Pentacam data, there were statistically significant differences between Groups 1 and 2 in all parameters except corneal volume (p<0.05). Group 1 and Group 3 were significantly different in all evaluated parameters (p<0.05). Steep keratometry, flat keratometry, mean keratometry, and posterior elevation (PE) were statistically similar between Groups 2 and 3 (p>0.05), while the other evaluated parameters differed significantly (p<0.05). ROC curve analysis showed that the difference in corneal thickness between the apex and thinnest point, PI, index of surface variance, index of height asymmetry and inferior-superior had the highest sensitivity and specificity in differentiating Group 2 from Group 3, while CCTapex, CCTmin, PE, and Rmin had the highest sensitivity and specificity in differentiating Group 2 from Group 1. Conclusion: In patients with unilateral keratoconus, fellow eyes appear to not be completely normal. Thus, it is recommended that fellow eyes also be evaluated in every examination of unilateral keratoconus patients.

Indexed as

AdolescentAdultCorneaCorneal TopographyFemaleFollow-Up StudiesHumansKeratoconusMaleMiddle AgedReproducibility of ResultsRetrospective StudiesROC CurveSeverity of Illness IndexYoung AdultAmsler-KrumeichScheimpflug cameraunilateral keratoconus

Identifiers

PMID31245968
PMCPMC6624469
OpenAlexW2955895425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.