ArticleJournal of biophotonics2019
Pilot feasibility study of in vivo intraoperative quantitative optical coherence tomography of human brain tissue during glioma resection.
Article in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 41 citations in OpenAlex.
- Emerging In Vivo Imaging Modalities for Improved Glioblastoma Surgery and Monitoring.Biomedicines · 2026Review
- Intraoperative Spectroscopic and Mass Spectrometric Assessment of Glioma Margins: A Systematic Review and Meta-Analysis.Cancers · 2026Review
- Advancements in Intraoperative Imaging for Enhanced Surgical Precision.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Leveraging pretrained vision transformers for automated cancer diagnosis in optical coherence tomography images.Biomedical optics express · 2025Article
- Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real-Time Tumor Grading and Large-Area Microvascular Imaging in Human Spinal Cord Surgery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Towards Optical Biopsy in Glioma Surgery.International journal of molecular sciences · 2025Review
- Review
- Accurate attenuation characterization in optical coherence tomography using multi-reference phantoms and deep learning.Biomedical optics express · 2024Article
- Attenuation coefficient as a tool to detect changes in the white matter of the rat brain caused by different types of gliomas and irradiation.Biomedical optics express · 2024Article
- Microscope integrated MHz optical coherence tomography system for neurosurgery: development and clinical in-vivo imaging.Biomedical optics express · 2024Article
- Label-free optical imaging for brain cancer assessment.Trends in cancer · 2024Review
- Theoretical and experimental determination of the confocal function of OCT systems for accurate calculation of sample optical properties.Biomedical optics express · 2024Article
- Confocal corrected attenuation coefficient imaging in phantoms andBiomedical optics express · 2023Article
- Mapping optical scattering properties to physical particle information in singly and multiply scattering samples.Biomedical optics express · 2023Article
- The neurosurgical benefit of contactlessFrontiers in oncology · 2023Article
- Functional imaging of the exposed brain.Frontiers in neuroscience · 2023Review
- Nondestructive label-free detection of peritumoral white matter damage using cross-polarization optical coherence tomography.Frontiers in oncology · 2023Article
- Brain white matter morphological structure correlation with its optical properties estimated from optical coherence tomography (OCT) data.Biomedical optics express · 2022Article
- Theranostic applications of optical coherence tomography in neurosurgery?Neurosurgical review · 2022Review
- OCT-Guided Surgery for Gliomas: Current Concept and Future Perspectives.Diagnostics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
This study investigates the feasibility of in vivo quantitative optical coherence tomography (OCT) of human brain tissue during glioma resection surgery in six patients. High-resolution detection of glioma tissue may allow precise and thorough tumor resection while preserving functional brain areas, and improving overall survival. In this study, in vivo 3D OCT datasets were collected during standard surgical procedure, before and after partial resection of the tumor, both from glioma tissue and normal parenchyma. Subsequently, the attenuation coefficient was extracted from the OCT datasets using an automated and validated algorithm. The cortical measurements yield a mean attenuation coefficient of 3.8 ± 1.2 mm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.