Evidence map›Paper›PMID 31245670›Full record

ArticlePlant direct2017

Members of the abscisic acid co-receptor PP2C protein family mediate salicylic acid-abscisic acid crosstalk.

Murli Manohar, Dekai Wang, Patricia M Manosalva, Hyong Woo Choi, Erich Kombrink, Daniel F Klessig

Open access · goldAbstract read
In one paragraph

Article in Plant direct, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Salicylic Acid in Root Growth and Development.International journal of molecular sciences · 2022
    Review
  15. Mapping of CaPP2C35 involved in the formation of light-green immature pepper (Capsicum annuum L.) fruits via GWAS and BSA.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Article
  16. Article
  17. Transcriptome Analysis of Needle and Root ofPlants (Basel, Switzerland) · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Murli ManoharBoyce Thompson Institute Cornell University Ithaca NY USA.
Dekai WangBoyce Thompson Institute Cornell University Ithaca NY USA.
Patricia M ManosalvaBoyce Thompson Institute Cornell University Ithaca NY USA.
Hyong Woo ChoiBoyce Thompson Institute Cornell University Ithaca NY USA.
Erich KombrinkChemical Biology Laboratory Max Plank Institute for Plant Breeding Research Cologne Germany.
Daniel F KlessigBoyce Thompson Institute Cornell University Ithaca NY USA.
Cornell University · USMax Planck Institute for Plant Breeding Research · DEZheJiang Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interplay between abscisic acid (ABA) and salicylic acid (SA) influences plant responses to various (a)biotic stresses; however, the underlying mechanism for this crosstalk is largely unknown. Here, we report that type 2C protein phosphatases (PP2Cs), some of which are negative regulators of ABA signaling, bind SA. SA binding suppressed the ABA-enhanced interaction between these PP2Cs and various ABA receptors belonging to the PYR/PYL/RCAR protein family. Additionally, SA suppressed ABA-enhanced degradation of PP2Cs and ABA-induced stabilization of SnRK2s. Supporting SA's role as a negative regulator of ABA signaling, exogenous SA suppressed ABA-induced gene expression, whereas the SA-deficient

Indexed as

ABA–SA crosstalkabiotic stressabscisic acidbiotic stresssalicylic acidtype 2C protein phosphatases

Identifiers

PMID31245670
PMCPMC6508495
OpenAlexW2949160826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.