Evidence map›Paper›PMID 31245642›Full record

ArticleHeliyon2019

The correlation between expression of sip protein in different serotypes of group b streptococcus and diagnosis.

Shiliang Cheng, Jiae Han, Yidan Huang, Qin Yan, Gang Lu, Zuowei Yuan, Guanjun Huang, Jian Zheng, Tianqiang Liu

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shiliang ChengClinical Laboratory (QILU Clinical Laboratory), Shandong Provincial Third Hospital, Ji'nan, Shandong, 250031, China.
Jiae HanClinical Laboratory, The People Hospital of Tianqiao District of Jinan, Shandong, 250031, China.
Yidan HuangArtron BioResearch Inc., Burnaby, British Columbia, V5J 5H6, Canada.
Qin YanArtron BioResearch Inc., Burnaby, British Columbia, V5J 5H6, Canada.
Gang LuArtron BioResearch Inc., Burnaby, British Columbia, V5J 5H6, Canada.
Zuowei YuanArtron BioResearch Inc., Burnaby, British Columbia, V5J 5H6, Canada.
Guanjun HuangNational and Local Joint Engineering Laboratory for Aquaculture Animal Disease Prevention and Control Technology, Chengdu, Sichuan, 610081, China.
Jian ZhengJinan Kangbo Biotechnology, 2766 Ying Xiu Road, Ji'nan, Shandong, 250101, China.
Tianqiang LiuNational and Local Joint Engineering Laboratory for Aquaculture Animal Disease Prevention and Control Technology, Chengdu, Sichuan, 610081, China.
Artron Bioresearch (Canada) · CAShandong Provincial Hospital · CNThe First People's Hospital of Tianmen · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the surface immunogenic protein (Sip) of group B streptococcus was identified, it's immunogenicity and its potential as a universal vaccine candidate has been evaluated extensively. We developed recombinant Sip protein and used it for monoclonal antibody generation to develop immunochromatographic test kit for GBS detection. The test of bacteria and culture media revealed the correlation between Sip protein expression and diagnosis discrepancy, which has never been reported. Furthermore, not only the surface accessibility of the Sip protein may vary from strains or serotypes; the secretion level of Sip protein may also vary.

Indexed as

BiochemistryImmunologyMicrobiology

Identifiers

PMID31245642
PMCPMC6581873
OpenAlexW2951135794

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.