Evidence map›Paper›PMID 31245629›Full record

ArticleJournal of psychiatry and brain science2019

Endophenotypes in Schizophrenia: Digging Deeper to Identify Genetic Mechanisms.

Tiffany A Greenwood, Andrew Shutes-David, Debby W Tsuang

Open access · diamondAbstract read
In one paragraph

Article in Journal of psychiatry and brain science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  11. Patterns of Impaired Neurocognitive Performance on the Global Neuropsychological Assessment, and Their Brain Structural Correlates in Recent-onset and Chronic Schizophrenia.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Tiffany A GreenwoodDepartment of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA.
Andrew Shutes-DavidGeriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Debby W TsuangGeriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA.
Geriatric Research Education and Clinical Center · USUniversity of California, San Diego · USUniversity of Washington · US

Funding

The Genetics of Endophenotypes and SchizophreniaR01MH065571 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRAFF, DAVID L. · 2003 to 2013
$7.0M
Genetics of Endophenotypes and SchizophreniaR01MH065558 · NIMH · UNIVERSITY OF WASHINGTON · PI TSUANG, DEBBY WEN · 2003 to 2013
$3.7M
Deep Sequencing in SchizophreniaI01BX002241 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI TSUANG, DEBBY WEN · 2014 to 2017
–
BLRD VA I01 BX002241NIMH NIH HHS R01 MH065558NIMH NIH HHS R01 MH065571
6 · The paper itself

Abstract

Schizophrenia (SZ) is a severe psychotic disorder that is highly heritable and common in the general population. The genetic heterogeneity of SZ is substantial, with contributions from common, rare, and

Indexed as

endophenotypegeneticsneurocognitionneurophysiologyschizophrenia

Identifiers

PMID31245629
PMCPMC6594566
OpenAlexW2935914202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.