Evidence map›Paper›PMID 31245530›Full record

ArticleInternational journal of cardiology. Heart & vasculature2019

Lipoprotein (a) level is associated with plaque vulnerability in patients with coronary artery disease: An optical coherence tomography study.

Yusuke Muramatsu, Yoshiyasu Minami, Ayami Kato, Aritomo Katsura, Toshimitsu Sato, Ryota Kakizaki, Teruyoshi Nemoto, Takuya Hashimoto, Kazuhiro Fujiyoshi, Kentaro Meguro and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05308329 (Kitasato Percutaneous Coronary Intervention Registry), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05308329 unknown statusnot on this map

Kitasato Percutaneous Coronary Intervention Registry

TypeobservationalSponsorKitasato UniversityRan2012 to 2025Enrolled4,500ConditionsAcute Coronary Syndrome, STEMI - ST-segment Elevation Myocardial Infarction, NSTEMI - Non-ST-Segment Elevation Myocardial Infarction, AtherosclerosisArmsIntra-coronary imaging device, PCI procedural characteristics
3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
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  7. Observational
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  9. Review
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  11. The Role of Cardiac Computed Tomography Angiography in Risk Stratification for Coronary Artery Disease.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Association of Lipoprotein(a) With Atherosclerotic Plaque Progression.Journal of the American College of Cardiology · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yusuke MuramatsuDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Yoshiyasu MinamiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Ayami KatoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Aritomo KatsuraDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Toshimitsu SatoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Ryota KakizakiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Teruyoshi NemotoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Takuya HashimotoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Kazuhiro FujiyoshiDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Kentaro MeguroDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Takao ShimohamaDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Junya AkoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigh lipoprotein (a) [Lp(a)] levels are an independent factor for worse prognosis in patients with coronary artery disease (CAD). However, the association between serum Lp(a) level and coronary plaque vulnerability remains to be determined.

methodsA total of 255 consecutive patients with CAD who underwent optical coherence tomography imaging of culprit lesions were included. Patients were divided into 2 groups according to their Lp(a) levels (the higher Lp(a) group [≥25 mg/dL],

resultsThe prevalence of thin-cap fibroatheroma (TCFA) was significantly higher in the higher Lp(a) group than in the lower Lp(a) group (23% [

conclusionsA higher Lp(a) level was associated with a higher frequency of TCFA, particularly in patients with a higher LDL-C level.

Identifiers

PMID31245530
PMCPMC6582072

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.