Data describing effects of perinatal exposure to bisphenol S on a peripubertal estrogen challenge in intact female CD-1 mice.

Sri Durga Devi Kolla, Laura N Vandenberg

Open access · goldAbstract read

In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 44% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Bisphenol S alters development of the male mouse mammary gland and sensitizes it to a peripubertal estrogen challenge.Toxicology · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sri Durga Devi KollaDepartment of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts - Amherst, 171C Goessmann, 686 N. Pleasant Street, Amherst, MA, 01003, USA.

Laura N VandenbergDepartment of Environmental Health Sciences, School of Public Health and Health Sciences, University of Massachusetts - Amherst, 171C Goessmann, 686 N. Pleasant Street, Amherst, MA, 01003, USA.

University of Massachusetts Amherst · US

Funding

Impact of Environmental Estrogens on Sexually Dimorphic Development of the Mouse Mammary GlandK22ES025811 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI VANDENBERG, LAURA N. · 2015 to 2017

$445k

NIEHS NIH HHS K22 ES025811

6 · The paper itself

Abstract

Bisphenol S (BPS) is an analogue of bisphenol A (BPA), used in consumer products including food packaging and thermal paper. Like BPA, BPS is an estrogen receptor agonist and exposures during perinatal development have been shown to alter growth and morphology of the mouse female mammary gland prior to puberty and in adulthood. Reported here are data describing the effect of exposure to low doses of BPS (2, 200 or 2000 μg/kg/day) during perinatal development on morphology and gene expression in the mammary gland of female CD-1 mice, with or without an additional estrogen exposure (1 μg/kg/day ethinyl estradiol) during the peripubertal period. Additional data document other estrogen-sensitive outcomes including timing of vaginal opening and uterine weight. The data suggest that low doses of BPS induce modest changes in the mammary gland at puberty, but do not appear to sensitize the female to an estrogenic challenge administered during the peripubertal period.

Indexed as

Endocrine disruptorMammary glandMorphometricPubertyTwo hit modelXenoestrogen

Identifiers

PMID31245508

DOI10.1016/j.dib.2019.103862

PMCPMC6582066

OpenAlexW2924915553

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.