Evidence map›Paper›PMID 31245453›Full record

ArticleRegenerative therapy2015

Regenerative therapy by fusion of medicine and engineering: First-in-human clinical trials with induced pluripotent stem cells and cell sheet technology: A report of the Symposium of Regenerative Medicine for Patients.

Teruo Okano, Yoshiki Sawa, Emma Barber, Akihiro Umezawa

Open access · goldAbstract read
In one paragraph

Article in Regenerative therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cell therapy for age-related macular degeneration.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Teruo OkanoJapanese Society of Regenerative Medicine, Tokyo, 112-0012, Japan.
Yoshiki SawaJapanese Society of Regenerative Medicine, Tokyo, 112-0012, Japan.
Emma BarberDepartment of Education for Clinical Research, National Research Institute for Child Health and Development, Tokyo, 157-8535, Japan.
Akihiro UmezawaJapanese Society of Regenerative Medicine, Tokyo, 112-0012, Japan.
National Center For Child Health and Development · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Symposium of Regenerative Medicine for Patients, organized by the Japanese Society for Regenerative Medicine, was held on 28 September 2014 in Tokyo, Japan. The event provided an overview of the important areas of cell-based medicine, and highlighted the first-in-human clinical trial of induced pluripotent stem cell (iPSC)-derived products. Recent advances in regenerative medicine were also discussed, especially regarding the use of somatic cells such as chondrocytes, skeletal myocytes and cardiomyocytes under both the Act on the Safety of Regenerative Medicine, and the Pharmaceuticals, Medical Devices and Other Therapeutic Products Act.

Indexed as

Act on the Safety of Regenerative MedicineCell sheet techniquesiPS cellsMacular degenerationMedical Devices and Other Therapeutic Products ActPharmaceuticalsRegenerative therapyRetinal pigmented epithelium (RPE)

Identifiers

PMID31245453
PMCPMC6581764
OpenAlexW2172679685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.