Evidence map›Paper›PMID 31245439›Full record

ArticleRegenerative therapy2015

Characterization of

Shinji Kusakawa, Kazuhiko Machida, Satoshi Yasuda, Nozomi Takada, Takuya Kuroda, Rumi Sawada, Hanayuki Okura, Hideki Tsutsumi, Shin Kawamata, Yoji Sato

Open access · goldAbstract read
In one paragraph

Article in Regenerative therapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Development of Animal Models for Preclinical Safety Studies.Advances in experimental medicine and biology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Evaluation of twoMolecular therapy. Methods & clinical development · 2021
    Article
  18. Review
  19. Spontaneous granulocytic leukemia in a NOD/Shi-Journal of toxicologic pathology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Shinji KusakawaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Kazuhiko MachidaTesting Department, Central Institute for Experimental Animals, Kawasaki, Japan.
Satoshi YasudaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Nozomi TakadaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Takuya KurodaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Rumi SawadaDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Hanayuki OkuraPlatform for Realization of Regenerative Medicine, Foundation for Biomedical Research and Innovation, Kobe, Japan.
Hideki TsutsumiTesting Department, Central Institute for Experimental Animals, Kawasaki, Japan.
Shin KawamataFoundation for Biomedical Research and Innovation, Kobe, Japan.
Yoji SatoDivision of Cell-Based Therapeutic Products, National Institute of Health Sciences, Tokyo, Japan.
Foundation for Biomedical Research and Innovation · JPCentral Institute for Experimental Animals · JPNational Institute of Health Sciences · JPNagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contamination of human cell-processed therapeutic products (hCTPs) with tumorigenic cells is one of the major concerns in the manufacturing and quality control of hCTPs. However, no quantitative method for detecting the tumorigenic cellular impurities is currently standardized. NOD/Shi-scid IL2Rγ

Indexed as

Cellular therapyNOG miceQuality controlRegenerative medicineTumorigenicity test

Identifiers

PMID31245439
PMCPMC6581766
OpenAlexW2066887344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.