Evidence map›Paper›PMID 31245364›Full record

ArticleFrontiers in bioengineering and biotechnology2019

High-Yield Production of 4-Hydroxybenzoate From Glucose or Glycerol by an Engineered

Christoph Lenzen, Benedikt Wynands, Maike Otto, Johanna Bolzenius, Philip Mennicken, Lars M Blank, Nick Wierckx

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. EngineeringMetabolic engineering communications · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Reliable Genomic Integration Sites inACS synthetic biology · 2024
    Article
  8. Metabolic bottlenecks ofMetabolic engineering communications · 2024
    Article
  9. Article
  10. Article
  11. Co-feeding enhances the yield of methyl ketones.Journal of industrial microbiology & biotechnology · 2023
    Article
  12. Metabolic engineering ofMetabolic engineering communications · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Characterization of Context-Dependent Effects on Synthetic Promoters.Frontiers in bioengineering and biotechnology · 2020
    Article
  18. Review
  19. Comparison of Three Xylose Pathways inFrontiers in bioengineering and biotechnology · 2019
    Article
  20. Frontiers in bioengineering and biotechnology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christoph LenzenInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Benedikt WynandsInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Maike OttoInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Johanna BolzeniusInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Philip MennickenInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Lars M BlankInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.
Nick WierckxInstitute of Applied Microbiology iAMB, RWTH Aachen University, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatic compounds such as 4-hydroxybenzoic acid are broadly applied in industry for a myriad of applications used in everyday life. However, their industrial production currently relies heavily on fossil resources and involves environmentally unfriendly production conditions, thus creating the need for more sustainable biotechnological alternatives. In this study, synthetic biology was applied to metabolically engineer

Indexed as

4-hydroxybenzoatearomaticsglycerolmetabolic engineeringPseudomonas taiwanensis VLB120shikimate pathwaysynthetic biology

Identifiers

PMID31245364
PMCPMC6581684

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.