Evidence map›Paper›PMID 31245038›Full record

ArticleFuture science OA2019

New UPLC-MS/MS assay for the determination of tamoxifen and its metabolites in human plasma, application to patients.

Christine Bobin-Dubigeon, Mario Campone, Elsa Rossignol, Estelle Salaun, Marie-Bernadette Amiand, Jean-Marie Bard

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future science OA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Christine Bobin-DubigeonBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Mario CamponeBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Elsa RossignolBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Estelle SalaunBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Marie-Bernadette AmiandBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Jean-Marie BardBiopathology Department ICO René Gauducheau, Bd J Monod, 44805 Nantes Saint Herblain Cedex, France.
Institut Génétique Nantes Atlantique · FRNantes Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimA rapid UPLC-MS/MS method for the determination of tamoxifen (TAM), MATERIALS AND

methodsThe analysis was achieved on a C

resultsThe validated method demonstrated good linearity between 1 and 500 ng/ml for TAM and

conclusionThe method is applied routinely for TAM monitoring from patients undergoing therapy.

Indexed as

4-hydroxytamoxifenanalytical methodendoxifenN desmethyl tamoxifenplasmatamoxifentherapeutic drug monitoringUPLC–MS/MSvalidation method

Identifiers

PMID31245038
PMCPMC6554689
OpenAlexW2923996890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.