Evidence map›Paper›PMID 31244927›Full record

ArticleTheranostics2019

Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.

Jiulong Zhao, Wei Gao, Xiaojun Cai, Jiajia Xu, Duowu Zou, Zhaoshen Li, Bing Hu, Yuanyi Zheng

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 224 citations in OpenAlex.

  1. Self-Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jiulong ZhaoShanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 (China).
Wei GaoDepartment of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 (China).
Xiaojun CaiShanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 (China).
Jiajia XuDepartment of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433 (China).
Duowu ZouDepartment of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433 (China).
Zhaoshen LiDepartment of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai 200433 (China).
Bing HuDepartment of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 (China).
Yuanyi ZhengShanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233 (China).
Shanghai Jiao Tong University · CNSecond Military Medical University · CNShanghai Sixth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS promote the initiation and progression of ulcerative colitis (UC). This study proposes a unique concept of nanomaterials with intrinsic enzyme-like activity (nanozymes) to mediate catalytic nanotherapy for IBD.

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsDisease Models, AnimalDrug CarriersFerrocyanidesFree Radical ScavengersHumansInflammatory Bowel DiseasesMiceNanostructuresReactive Oxygen SpeciesTreatment OutcomeAnti-Inflammatory AgentsAntioxidantsDrug Carriersferric ferrocyanideFerrocyanidesFree Radical ScavengersReactive Oxygen Speciesinflammatory bowel diseasemanganese Prussian bluemulti-enzyme activitynanozymereactive oxygen species

Identifiers

PMID31244927
PMCPMC6568174
OpenAlexW2935723172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.