Evidence map›Paper›PMID 31244887›Full record

ArticleFrontiers in genetics2019

The Effect of Genetic Variation on the Placental Transcriptome in Humans.

Triin Kikas, Kristiina Rull, Robin N Beaumont, Rachel M Freathy, Maris Laan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Placental Origins of Preeclampsia: Insights from Multi-Omic Studies.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Triin KikasHuman Genetics Research Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Kristiina RullHuman Genetics Research Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Robin N BeaumontInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.
Rachel M FreathyInstitute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.
Maris LaanHuman Genetics Research Group, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
University of Exeter · GBUniversity of Tartu · EETartu University Hospital · EE

Funding

Medical Research Council G9815508Medical Research Council MC_PC_19009Wellcome Trust
6 · The paper itself

Abstract

The knowledge of genetic variants shaping human placental transcriptome is limited and they are not cataloged in the Genotype-Tissue Expression project. So far, only one whole genome analysis of placental expression quantitative trait loci (eQTLs) has been published by Peng et al. (2017) with no external independent validation. We report the second study on the landscape of placental eQTLs. The study aimed to generate a high-confidence list of placental

Indexed as

ALSPACcis-eQTLcomplex traitsHAPPY PREGNANCYhuman placentaREPROMETA

Identifiers

PMID31244887
PMCPMC6581026
OpenAlexW2952205756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.