ArticleFrontiers in immunology2019
Individual Sea Urchin Coelomocytes Undergo Somatic Immune Gene Diversification.
Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 57 citations in OpenAlex.
- How and when organisms edit their own genomes.Nature genetics · 2025Review
- The resistance awakens: Diversity at the DNA, RNA, and protein levels informs engineering of plant immune receptors from Arabidopsis to crops.The Plant cell · 2025Review
- Review
- Local Genomic Instability of theGenes · 2024Article
- Recombinant SpTransformer proteins are functionally diverse for binding and phagocytosis by three subtypes of sea urchin phagocytes.Frontiers in immunology · 2024Article
- The characterization of toll-like receptor repertoire inEcology and evolution · 2023Article
- Editorial: Women in comparative immunology.Frontiers in immunology · 2023Article
- The mechanisms and factors that induce trained immunity in arthropods and mollusks.Frontiers in immunology · 2023Review
- The complex set of internal repeats in SpTransformer protein sequences result in multiple but limited alternative alignments.Frontiers in immunology · 2022Article
- Review
- Coelomocyte populations in the sea urchin,Frontiers in immunology · 2022Article
- Different sea urchin RAG-like genes were domesticated to carry out different functions.Frontiers in immunology · 2022Article
- Echinochrome A Treatment Alleviates Atopic Dermatitis-like Skin Lesions in NC/Nga Mice via IL-4 and IL-13 Suppression.Marine drugs · 2021Article
- The Diverse Transformer (Trf) Protein Family in the Sea UrchinInternational journal of molecular sciences · 2021Article
- Evolution of thymopoietic microenvironments.Open biology · 2021Review
- Guardian of the Genome: An Alternative RAG/Transib Co-Evolution Hypothesis for the Origin of V(D)J Recombination.Frontiers in immunology · 2021Article
- Editorial: Immunity in Marine Invertebrates: Integrating Transcriptomics to Proteomics and Metabolomics.Frontiers in immunology · 2021Article
- Sequence Diversity, Locus Structure, and Evolutionary History of theFrontiers in immunology · 2021Article
- Evolutionary perspective on the hematopoietic system through a colonial chordate: allogeneic immunity and hematopoiesis.Current opinion in immunology · 2020Review
- Beyond Adult Stem Cells: Dedifferentiation as a Unifying Mechanism Underlying Regeneration in Invertebrate Deuterostomes.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adaptive immune response in jawed vertebrates is marked by the ability to diversify somatically specific immune receptor genes. Somatic recombination and hypermutation of gene segments are used to generate extensive repertoires of T and B cell receptors. In contrast, jawless vertebrates utilize a distinct diversification system based on copy choice to assemble their variable lymphocyte receptors. To date, very little evidence for somatic immune gene diversification has been reported in invertebrate species. Here we show that the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.