Evidence map›Paper›PMID 31244831›Full record

ReviewFrontiers in immunology2019

An Essential Role of Innate Lymphoid Cells in the Pathophysiology of Graft-vs.-Host Disease.

Liang Shao, Shan Pan, Qiu-Ping Zhang, Muhammad Jamal, Lu-Hua Chen, Qian Yin, Ying-Jie Wu, Jie Xiong, Rui-Jing Xiao, Yok-Lam Kwong and 2 more

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. The Role of Group 3 Innate Lymphoid Cells in Lung Infection and Immunity.Frontiers in cellular and infection microbiology · 2021
    Review
  9. Macrophage regulation of graft-World journal of clinical cases · 2020
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Liang ShaoDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shan PanDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Qiu-Ping ZhangDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Muhammad JamalDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Lu-Hua ChenDepartment of Medicine, Li Ka Shing Faculty of Medicine, Faculty of Social Sciences, The University of Hong Kong, Hong Kong, China.
Qian YinDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Ying-Jie WuDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Jie XiongDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Rui-Jing XiaoDepartment of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Yok-Lam KwongDivision of Hematology & BMT Center, Queen Mary Hospital, Hong Kong, China.
Fu-Ling ZhouDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Albert K W LieDivision of Hematology & BMT Center, Queen Mary Hospital, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is the only curative treatment for multiple hematologic malignancies and non-malignant hematological diseases. However, graft-vs.-host disease (GVHD), one of the main complications after allo-HSCT, remains the major reason for morbidity and non-relapse mortality. Emerging evidence has demonstrated that innate lymphoid cells (ILCs) play a non-redundant role in the pathophysiology of GVHD. In this review, we will summarize previously published data regarding the role of ILCs in the pathogenesis of GVHD.

Indexed as

Disease SusceptibilityImmunity, InnateBiomarkersCell PlasticityGene Expression RegulationGraft vs Host DiseaseHumansImmunophenotypingKiller Cells, NaturalLymphocytesT-LymphocytesTranscription, GeneticBiomarkersgraft-vs.-host diseasehematopoietic stem cell transplantationILCreginnate lymphoid cellsNK cellsT cells

Identifiers

PMID31244831
PMCPMC6563595

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.