Evidence map›Paper›PMID 31244818›Full record

ArticleFrontiers in microbiology2019

Characterization of Mucosa-Associated Microbiota in Matched Cancer and Non-neoplastic Mucosa From Patients With Colorectal Cancer.

Polly H M Leung, Rao Subramanya, Qianqian Mou, Katherine Ting-Wei Lee, Farhadul Islam, Vinod Gopalan, Cu-Tai Lu, Alfred King-Yin Lam

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Association ofGut microbiome (Cambridge, England) · 2025
    Review
  14. Investigation of the relationship betweenFrontiers in microbiology · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Exploring the interplay betweenFrontiers in microbiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Polly H M LeungDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Rao SubramanyaDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Qianqian MouDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.
Katherine Ting-Wei LeePathology, School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, QLD, Australia.
Farhadul IslamPathology, School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, QLD, Australia.
Vinod GopalanPathology, School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, QLD, Australia.
Cu-Tai LuDepartment of Surgery, Gold Coast University Hospital, Gold Coast, QLD, Australia.
Alfred King-Yin LamPathology, School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, QLD, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colonic microbiota play important roles in the development of colorectal cancer. We aim to characterise the mucosa-associated microbiota in the tumour as well as the matched non-neoplastic mucosa from patients with colorectal cancer. Microbiota profiling in these samples was done using high-throughput 16S rRNA amplicon sequencing. Our results showed that the microbiota richness and diversity were similar between the tumour and non-neoplastic mucosae. Linear discriminant analysis effect size (LEfSe) analysis identified

Indexed as

16S rRNA amplicon sequencingBrevundimonascolorectal cancerdysbiosisFusobacteriummucosa-associated microbiota

Identifiers

PMID31244818
PMCPMC6581718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.