Evidence map›Paper›PMID 31244787›Full record

ArticleFrontiers in microbiology2019

Antibiotic-Producing Beneficial Bacteria in the Gut of the Burying Beetle

Philipp Heise, Yang Liu, Thomas Degenkolb, Heiko Vogel, Till F Schäberle, Andreas Vilcinskas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Reconstruction of Gut Bacteria inJournal of fungi (Basel, Switzerland) · 2023
    Article
  9. Unraveling the Role of Antimicrobial Peptides in Insects.International journal of molecular sciences · 2023
    Review
  10. Comparative Nanopore Sequencing-Based Evaluation of the Midgut Microbiota of the Summer Chafer (International journal of environmental research and public health · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Bacterial Inhibition onFrontiers in microbiology · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Philipp HeiseDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Giessen, Germany.
Yang LiuInstitute for Insect Biotechnology, Justus Liebig University Giessen, Giessen, Germany.
Thomas DegenkolbInstitute for Insect Biotechnology, Justus Liebig University Giessen, Giessen, Germany.
Heiko VogelDepartment of Entomology, Max Planck Institute for Chemical Ecology, Jena, Germany.
Till F SchäberleDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Giessen, Germany.
Andreas VilcinskasDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology, Giessen, Germany.
Fraunhofer Institute for Molecular Biology and Applied Ecology · DEJustus-Liebig-Universität Gießen · DEMax Planck Institute for Chemical Ecology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of antibiotic-resistant human pathogens is a growing public concern and there is intense pressure to identify new antibacterial compounds that can be developed into antibiotics with novel mode of action. Evolutionary theory predicts that insects that have evolved to occupy sophisticated ecological niches by feeding and reproducing on carcasses will depend on their gut microbiome to prevent colonization by invading pathogens taken up with the diet. This inspired our hypothesis that the complex interactions between the core microbiome and the more flexible microbial communities dependent on the environment may promote the outsourcing of antibiotic synthesis to beneficial microbes. We tested this hypothesis by cultivating and characterizing bacteria isolated from the gut of the burying beetle

Indexed as

bioactivity-guided screeningburying beetlegut microbiomenatural productsnematodesNicrophorus vespilloidesserrawettin W2symbiosis

Identifiers

PMID31244787
PMCPMC6563848
OpenAlexW2947230268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.