ReviewFrontiers in endocrinology2019
Environmental Cycles, Melatonin, and Circadian Control of Stress Response in Fish.
Review in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 140 citations in OpenAlex.
- Convergent latitudinal erosion of circadian systems in a rapidly diversifying order of fishes.PLoS genetics · 2026Article
- Physiological and Proteomic Insights into Melatonin-Mediated Regulation of Copper Toxicity in the CrayfishInternational journal of molecular sciences · 2026Article
- Feeding and light cycle disruptions have distinct effects on energy balance and neuroendocrine regulators in goldfish.Fish physiology and biochemistry · 2026Article
- Impacts of Long-Term High-Temperature and Low-Salinity Stress on the Circadian Rhythms of Antioxidant, Immune, and Endocrine Systems in Turbot (Antioxidants (Basel, Switzerland) · 2026Article
- Artificial light at night suppresses the metabolic response of a coral reef fish to a virtual predator.Conservation physiology · 2026Article
- Emergence of appetite and circadian rhythmicity in Atlantic salmon brain transcriptome from endogenous to exogenous feeding.PloS one · 2026Article
- Melatonin supplementation alleviates stocking-density stress and enhances growth, immune, and physiological performance of Sparus aurata cultured in groundwater-based systems.Veterinary research communications · 2025Article
- Antioxidant Defenses in the Kidneys and Heart of the Freshwater Fish Astyanax lacustris Subjected to High (31°C) and Low (15°C) Temperatures.Cell biochemistry and function · 2025Article
- Temperature and photoperiod stress in zebrafish larvae: impacts on development, gene regulation and PGC migration.Fish physiology and biochemistry · 2025Article
- Effects of Underwater Noise Exposure on Early Development in Zebrafish.Animals : an open access journal from MDPI · 2025Article
- Zebrafish as a Model Organism for Post-Traumatic Stress Disorder: Insights into Stress Mechanisms and Behavioral Assays.Biology · 2025Review
- Molecular Characterization and Feeding-Associated Expression Dynamics of the Period Gene Family in Channel Catfish (Current issues in molecular biology · 2025Article
- Disrupted darkness: the impact of anthropogenic light at night on melatonin secretion of Hermodice carunculata (Polychaeta, Annelida).Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Integration of photoperiod and time-restricted feeding on the circadian gene rhythms in juvenile salmon.Scientific reports · 2025Article
- Artificial light at night during early development directly affects embryonic but not larval quality in a wild coral reef fish.Conservation physiology · 2025Article
- Antagonistic interaction between caffeine and ketamine in zebrafish: Implications for aquatic toxicity.Environmental science and ecotechnology · 2024Article
- Exploration of the Synergistic Regulation Mechanism in Cerebral Ganglion and Heart ofAntioxidants (Basel, Switzerland) · 2024Article
- Early stress exposure on zebrafish development: effects on survival, malformations and molecular alterations.Fish physiology and biochemistry · 2024Article
- The effects of environmental changes on the endocrine regulation of feeding in fishes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Circadian rhythm in turbot (Scophthalmus maximus): daily variation of blood metabolites in recirculating aquaculture systems.Metabolomics : Official journal of the Metabolomic Society · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fish have evolved a biological clock to cope with environmental cycles, so they display circadian rhythms in most physiological functions including stress response. Photoperiodic information is transduced by the pineal organ into a rhythmic secretion of melatonin, which is released into the blood circulation with high concentrations at night and low during the day. The melatonin rhythmic profile is under the control of circadian clocks in most fish (except salmonids), and it is considered as an important output of the circadian system, thus modulating most daily behavioral and physiological rhythms. Lighting conditions (intensity and spectrum) change in the underwater environment and affect fish embryo and larvae development: constant light/darkness or red lights can lead to increased malformations and mortality, whereas blue light usually results in best hatching rates and growth performance in marine fish. Many factors display daily rhythms along the hypothalamus-pituitary-interrenal (HPI) axis that controls stress response in fish, including corticotropin-releasing hormone (Crh) and its binding protein (Crhbp), proopiomelanocortin A and B (Pomca and Pomcb), and plasma cortisol, glucose, and lactate. Many of these circadian rhythms are under the control of endogenous molecular clocks, which consist of self-sustained transcriptional-translational feedback loops involving the cyclic expression of circadian clock genes (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.