Evidence map›Paper›PMID 31244663›Full record

ArticleFrontiers in pharmacology2019

Star Allele-Based Haplotyping versus Gene-Wise Variant Burden Scoring for Predicting 6-Mercaptopurine Intolerance in Pediatric Acute Lymphoblastic Leukemia Patients.

Yoomi Park, Hyery Kim, Jung Yoon Choi, Sunmin Yun, Byung-Joo Min, Myung-Eui Seo, Ho Joon Im, Hyoung Jin Kang, Ju Han Kim

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04770922 (Pharmacogenomic Analysis of 6-mercaptopurine in Pediatric Acute Lymphoblastic Leukemia), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04770922 completednot on this mapstarted 2021, after this paper: background citation

Pharmacogenomic Analysis of 6-mercaptopurine in Pediatric Acute Lymphoblastic Leukemia

TypeobservationalSponsorCipherome, Inc.Ran2021 to 2021Enrolled80ConditionsAcute Lymphoblastic Leukemia, Pediatric, Adverse Drug Event
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoomi ParkSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, South Korea.
Hyery KimDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Jung Yoon ChoiDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Sunmin YunSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, South Korea.
Byung-Joo MinSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, South Korea.
Myung-Eui SeoSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, South Korea.
Ho Joon ImDepartment of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Hyoung Jin KangDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Ju Han KimSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

6-mercaptopurinedrug toxicitynext-generation sequencingNudix Hydrolase 15 (NUDT15)pharmacogeneticspharmacogenomicsThiopurine S-Methyltransferase (TPMT)variant burden

Identifiers

PMID31244663
PMCPMC6580331

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.