Evidence map›Paper›PMID 31244471›Full record

ArticleeLife2019

Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'.

Nils Landegren, Lindsey B Rosen, Eva Freyhult, Daniel Eriksson, Tove Fall, Gustav Smith, Elise M N Ferre, Petter Brodin, Donald Sharon, Michael Snyder and 3 more

Open access · goldAbstract readComment
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Nils LandegrenDepartment of Medicine (Solna), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-6163-9540
Lindsey B RosenLaboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Eva FreyhultDepartment of Medical Sciences, National Bioinformatics Infrastructure, Uppsala, Sweden.
Daniel ErikssonDepartment of Medicine (Solna), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-5473-3312
Tove FallDepartment of Medical Sciences, Molecular Epidemiology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Gustav SmithDepartment of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.
Elise M N FerreLaboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.ORCID 0000-0002-3285-7768
Petter BrodinDepartment of Cardiology, Clinical Sciences, Lund University, Skåne University Hospital, Lund, Sweden.ORCID 0000-0002-8103-0046
Donald SharonDepartment of Genetics, School of Medicine, Stanford University, Stanford, United States.
Michael SnyderWallenberg Center for Molecular Medicine, Lund University Diabetes Center, Lund University, Lund, Sweden.
Michail LionakisLaboratory of Clinical Immunology & Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, United States.
Mark AndersonDiabetes Center, University of California, San Francisco, San Francisco, United States.
Olle KämpeDepartment of Medicine (Solna), Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-6091-9914
Karolinska University Hospital · SENational Institutes of Health · USUppsala University · SEBroad Institute · USLund University · SEStanford University · USUniversity of California, San Francisco · US

Funding

Immunopathogenesis of Fungal InfectionsZIAAI001175 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LIONAKIS, MICHAIL · 2012 to 2025
$23.9M
6 · The paper itself

Abstract

The

Indexed as

Diabetes Mellitus, Type 1Interferon Type IPolyendocrinopathies, AutoimmuneAutoantibodiesHumansTranscription FactorsAutoantibodiesInterferon Type ITranscription FactorsAPS1/APECEDautoantibodyautoantigenhumanhuman biologyimmune toleranceimmunologyinflammationmedicinetype 1 diabetes

Identifiers

PMID31244471
PMCPMC6597240
OpenAlexW2954062075

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.