Evidence map›Paper›PMID 31244158›Full record

ArticleThe Journal of organic chemistry2019

Peyssonnosides A-B, Unusual Diterpene Glycosides with a Sterically Encumbered Cyclopropane Motif: Structure Elucidation Using an Integrated Spectroscopic and Computational Workflow.

Bhuwan Khatri Chhetri, Serge Lavoie, Anne Marie Sweeney-Jones, Nazia Mojib, Vijay Raghavan, Kerstin Gagaring, Brandon Dale, Case W McNamara, Katy Soapi, Cassandra L Quave and 2 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Biosynthesis of the Red Algal Diterpene Peyssonnosol in Bacteria.Angewandte Chemie (International ed. in English) · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Catalysis-Enabled 13-Step Total Synthesis of (-)-Peyssonnoside A.Journal of the American Chemical Society · 2022
    Article
  9. Article
  10. Total syntheses of strained polycyclic terpenes.Chemical communications (Cambridge, England) · 2022
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Bhuwan Khatri Chhetri
Serge LavoieInstitut des Sciences de la Forêt Tempérée , Université du Québec en Outaouais , 58, rue Principale , Ripon , Québec J0V 1V0 , Canada.ORCID 0000-0002-7792-9737
Anne Marie Sweeney-Jones
Nazia Mojib
Vijay RaghavanDepartment of Chemistry , Vanderbilt University , Nashville , Tennessee 37235 , United States.
Kerstin GagaringCalibr at The Scripps Research Institute , La Jolla , California 92037 , United States.
Brandon DaleDepartment of Dermatology, Center for the Study of Human Health, and Antibiotic Resistance Center , Emory University , Atlanta , Georgia 30322 , United States.
Case W McNamaraCalibr at The Scripps Research Institute , La Jolla , California 92037 , United States.
Katy SoapiInstitute of Applied Sciences , University of South Pacific , Suva , Fiji.
Cassandra L QuaveDepartment of Dermatology, Center for the Study of Human Health, and Antibiotic Resistance Center , Emory University , Atlanta , Georgia 30322 , United States.
Prasad L PolavarapuDepartment of Chemistry , Vanderbilt University , Nashville , Tennessee 37235 , United States.ORCID 0000-0001-6458-0508
Julia KubanekParker H. Petit Institute for Bioengineering and Bioscience , Georgia Institute of Technology , Atlanta , Georgia 30332 , United States.ORCID 0000-0003-4482-1831
Georgia Institute of Technology · USEmory University · USScripps Research Institute · USVanderbilt University · USUniversité du Québec en Outaouais · CAUniversity of the South Pacific · FJ

Funding

Exploration, conservation, & development of marine biodiversity in FijiU01TW007401 · FIC · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAY, MARK E · 2005 to 2013
$7.4M
The USP Center for Drug Discovery and ConservationU19TW007401 · FIC · GEORGIA INSTITUTE OF TECHNOLOGY · PI HAY, MARK E · 2014 to 2018
$5.3M
FIC NIH HHS U01 TW007401FIC NIH HHS U19 TW007401
6 · The paper itself

Abstract

Two sulfated diterpene glycosides featuring a highly substituted and sterically encumbered cyclopropane ring have been isolated from the marine red alga Peyssonnelia sp. Combination of a wide array of 2D NMR spectroscopic experiments, in a systematic structure elucidation workflow, revealed that peyssonnosides A-B (1-2) represent a new class of diterpene glycosides with a tetracyclo [7.5.0.0

Indexed as

Aquatic OrganismsDiterpenesGlycosidesModels, MolecularMolecular StructureRhodophytaSpectrum AnalysisDiterpenesGlycosides

Identifiers

PMID31244158
PMCPMC6614789
OpenAlexW2949035169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.