Evidence map›Paper›PMID 31244054›Full record

ArticleACS chemical neuroscience2019

Cholesterol Biosynthesis and Uptake in Developing Neurons.

Thiago C Genaro-Mattos, Allison Anderson, Luke B Allen, Zeljka Korade, Károly Mirnics

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 106 citations in OpenAlex.

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  5. Metabolic trajectories in developing human neocortical neurons.Proceedings of the National Academy of Sciences of the United States of America · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thiago C Genaro-MattosMunroe-Meyer Institute for Genetics and Rehabilitation , University of Nebraska Medical Center , Omaha , Nebraska 68105 , United States.
Allison AndersonMunroe-Meyer Institute for Genetics and Rehabilitation , University of Nebraska Medical Center , Omaha , Nebraska 68105 , United States.
Luke B AllenDepartment of Pediatrics, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
Zeljka KoradeDepartment of Pediatrics, College of Medicine , University of Nebraska Medical Center , Omaha , Nebraska 68198 , United States.
Károly MirnicsMunroe-Meyer Institute for Genetics and Rehabilitation , University of Nebraska Medical Center , Omaha , Nebraska 68105 , United States.ORCID 0000-0002-5521-0254
Nebraska Medical Center · USUniversity of Nebraska Medical Center · US

Funding

Neocortical Transcriptome Changes in SchizophreniaR01MH067234 · NIMH · VANDERBILT UNIVERSITY · PI MIRNICS, KAROLY · 2003 to 2021
$4.7M
SLOS and Neuronal Oxidative StressR01HD064727 · NICHD · VANDERBILT UNIVERSITY · PI PORTER, NED ALLEN · 2010 to 2020
$3.7M
Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone treatmentR01MH110636 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MIRNICS, KAROLY, PORTER, NED ALLEN · 2017 to 2021
$2.7M
NICHD NIH HHS R01 HD064727NIMH NIH HHS R01 MH067234NIMH NIH HHS R01 MH110636
6 · The paper itself

Abstract

Brain cholesterol biosynthesis, a separate and distinct process from whole-body cholesterol homeostasis, starts during embryonic development. To gain a better understanding of the neuronal and glial contributions to the brain cholesterol pool, we studied this process in control,

Indexed as

AnimalsAstrocytesBiological TransportBrainCholesterolChromatography, LiquidMiceNeuronsSterolsTandem Mass SpectrometryCholesterolSterolsastrocytescholesteroldesmosteroldeveloping neuronsDhcr24Dhcr7LC-MS/MSSterol biosynthesis

Identifiers

PMID31244054
PMCPMC7184320
OpenAlexW2950398114

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.