ArticleACS sensors2019
Selective and Sensocompatible Electrochemical Nitric Oxide Sensor with a Bilaminar Design.
Article in ACS sensors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Wound state monitoring by multiplexed, electrochemical, real-time, localized, inflammation-tracking nitric oxide sensor (MERLIN).Science advances · 2025Article
- Electrochemical Detection of Gasotransmitters: Status and Roadmap.ACS sensors · 2024Review
- Graphene nanocomposites for real-time electrochemical sensing of nitric oxide in biological systems.Applied physics reviews · 2023Article
- Planar carbon electrodes for real-time quantification of hydrogen sulfide release from cells.Sensors & diagnostics · 2023Article
- New trends in enzyme-free electrochemical sensing of ROS/RNS. Application to live cell analysis.Mikrochimica acta · 2022Review
- Silica Xerogel Doped with Iron(III) as Sensor Material for Salicylhydroxamic Acid Determination in Urine.Gels (Basel, Switzerland) · 2021Article
- Article
- Quantitative determination of nitric oxide from tissue samples using liquid chromatography-Mass spectrometry.MethodsX · 2021Article
- Mode of nitric oxide delivery affects antibacterial action.ACS biomaterials science & engineering · 2020Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Macrophages mediate mammalian inflammation in part by the release of the gasotransmitter, nitric oxide (NO). Electrochemical methods represent the best means of direct, continuous measurement of NO, but monitoring continuous release from immunostimulated macrophages remains analytically challenging. Long release durations necessitate consistent sensor performance (i.e., sensitivity and selectivity for NO) in proteinaceous media. Herein, we describe the fabrication of an electrochemical sensor modified by an electropolymerized 5-amino-1-naphthol (poly(5A1N)) film in conjunction with a fluorinated xerogel topcoat. The unique combination of these membranes ensures selective detection of NO that is maintained over extended periods of use (>24 h) in biological media without performance deterioration. The hydrophobic xerogel topcoat protects the underlying NO-selective poly(5A1N) film from hydration-induced desorption. The bilaminar sensor is then readily adapted for measurement of the temporal NO-release profiles from immunostimulated macrophages.
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Registered trials
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