Evidence map›Paper›PMID 31243670›Full record

ArticleJournal of natural medicines2020

Chemical components from the twigs of Caesalpinia latisiliqua and their antiviral activity.

Mira Oh, SeonJu Park, Jae-Hyoung Song, Hyun-Jeong Ko, Seung Hyun Kim

Abstract read
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In one paragraph

Article in Journal of natural medicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Two New Seco-Labdane Diterpenoids from the Leaves ofMolecules (Basel, Switzerland) · 2022
    Article
  4. Review
  5. Natural and nature-inspired stilbenoids as antiviral agents.European journal of medicinal chemistry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mira OhCollege of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea.
SeonJu ParkCollege of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea.
Jae-Hyoung SongCollege of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Hyun-Jeong KoCollege of Pharmacy, Kangwon National University, Chuncheon, South Korea.
Seung Hyun KimCollege of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, South Korea. kimsh11@yonsei.ac.kr.

Funding

Ministry of Education, Science and Technology NRF-2016R1A2B4006742Ministry of Education, Science and Technology University-
6 · The paper itself

Abstract

Three new compounds, (3S)-dihydrobonducellin 8-O-β-D-glucopyranoside (1), 3',5'-dimethoxy-jezonolid (2), and latisilinoid (3), along with 16 known compounds, were isolated from the twigs of Caesalpinia latisiliqua (Leguminosae). The known compounds were identified as flavonoids, stilbenes, and phenolics as determined by extensive spectroscopic methods, including 1D and 2D NMR. All the isolated compounds were evaluated for their antiviral activity in HRV1B-, CVB3-, and EV71-infected cells. Among the tested compounds, three flavonoids (4-6) and two stilbenes (12 and 14) exhibited significant antiviral activity. This is the first phytochemical investigation of C. latisiliqua twigs.

Indexed as

Antiviral AgentsCaesalpiniaPlantsAntiviral AgentsAntiviral activityCaesalpinia latisiliquaHomoisoflavonoidLeguminosaeStilbenoid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.