ArticleTechniques in coloproctology2019
Practice parameters for the diagnosis and treatment of anal intraepithelial neoplasia (AIN) on behalf of the Italian Society of Colorectal Surgery (SICCR).
Article in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Comparing and contrasting clinical consensus and guidelines for anal intraepithelial neoplasia in different geographical regions.Updates in surgery · 2021Pooled it
- Evaluating the efficacy of treatment options for anal intraepithelial neoplasia: a systematic review.International journal of colorectal disease · 2021Pooled it
- Genotyping and Cytology Co-Testing for Anal Cancer Screening: Exploratory Evaluation of Cumulative HPV Genotype Burden as a New Potential Marker for Risk Stratification.Diagnostics (Basel, Switzerland) · 2026Article
- Anal High-Grade Squamous Intraepithelial Lesions in People Living with HIV: A Systematic Review of Treatment Outcomes.Cancers · 2026Review
- Anal intraepithelial neoplasia in Ireland: practice patterns and the case for regionalisation.Irish journal of medical science · 2026Article
- Anal high-grade squamous intraepithelial lesions: identification, classification, and management.The British journal of surgery · 2026Review
- Radiation therapy in anal high-grade squamous intraepithelial lesions-a pattern of care analysis in German-speaking countries.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- PAP-HPV Co-Testing in Anal Cancer Screening: An Italian Experience.Journal of clinical medicine · 2025Article
- Clinical application of endoscopic submucosal dissection for superficially invasive squamous cell carcinoma/high-grade squamous intraepithelial lesion involving the canal anal.Techniques in coloproctology · 2024Article
- Screening for precancerous anal lesions linked to human papillomaviruses: French recommendations for clinical practice.Techniques in coloproctology · 2024Review
- The Clinical Utility of Circulating HPV DNA Biomarker in Oropharyngeal, Cervical, Anal, and Skin HPV-Related Cancers: A Review.Pathogens (Basel, Switzerland) · 2023Review
- Anal Cancer in High-Risk Women: The Lost Tribe.Cancers · 2022Review
- Outcomes of radiofrequency ablation for anal high-grade squamous intraepithelial lesions.Techniques in coloproctology · 2021Article
- Reorganization of the endoscopic activity of Cancer Institutes during phase II of the Covid-19 emergency.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2020Article
- Do we really need guidelines for HRA during the COVID-19 pandemic?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2020Article
- Recommendations Favoring Anal Cytology as a Method for Anal Cancer Screening: A Systematic Review.Cancers · 2019Review
- Improving outcomes for the treatment of Anal Squamous Cell Carcinoma and Anal Intraepithelial Neoplasia.Techniques in coloproctology · 2019Article
- Evaluation of hTERT Gene Expression and Chromosome 7 Copy Number Variation in Anal Squamous Intra-Epithelial Lesions: A Pilot Study.Journal of cytologyArticle
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Squamous cell carcinoma (SCC) of the anus is a human papilloma virus (HPV) related malignancy that is preceded by anal intraepithelial neoplasia (AIN) making this cancer, at least theoretically, a preventable disease. In the past 10 years the diagnosis, management and nomenclature of AIN has dramatically changed. Increased life expectancy in human immunodeficiency virus (HIV) positive patients due to highly active antiretroviral therapy (HAART) has caused an increase in the incidence of SCC of the anus. While many experts recommend screening and treatment of anal high-grade squamous intraepithelial lesion (HSIL), there is no consensus on the optimal management these lesions. Therefore, there is a need to review the current evidence on diagnosis and treatment of AIN and formulate recommendations to guide management. Surgeons who are members of the Italian Society of Colorectal Surgery (SICCR) with a recognized interest in AIN were invited to contribute on various topics after a comprehensive literature search. Levels of evidence were classified using the Oxford Centre for Evidence-based Medicine of 2009 and the strength of recommendation was graded according to the United States (US) preventive services task force. These recommendations are among the few entirely dedicated only to the precursors of SCC of the anus and provide an evidence-based summary of the current knowledge about the management of AIN that will serve as a reference for clinicians involved in the treatment of patients at risk for anal cancer.
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