Evidence map›Paper›PMID 31243587›Full record

ReviewCurrent cardiology reports2019

Assessment of Myocarditis: Cardiac MR, PET/CT, or PET/MR?

Wengen Chen, Jean Jeudy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Brazilian Society of Cardiology Guideline on Myocarditis - 2022.Arquivos brasileiros de cardiologia · 2022
    Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
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  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Myocarditis Following COVID-19 Vaccination.Heart failure clinics · 2023
    Review
  18. Review
  19. Review
  20. How Does COVID-19 Affect the Heart?Current cardiology reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wengen ChenDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD, 21201, USA. wchen5@umm.edu.
Jean JeudyDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, MD, 21201, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewDiagnosis of myocarditis is challenging given its variable clinical manifestations and non-specific laboratory findings. Cardiac magnetic resonance (MR) is currently the preferred imaging modality for the diagnosis of myocarditis. RECENT

findingsThe Lake Louis Criteria (CLL) of cardiac MR is widely used for the diagnosis of myocarditis. It has an overall acceptable sensitivity of 67% and specificity of 91% for acute myocarditis but does not have the same accuracy for chronic myocarditis. FDG PET/CT is capable of assessing myocarditis by providing metabolic information of inflammation as increased myocardial FDG uptake. In addition to reduced radiation exposure, FDG PET performed on a hybrid PET/MR may detect more myocarditis than FDG PET/CT, because of the delayed PET acquisition time on PET/MR. Case-based observations and small clinical studies of FDG PET/MR have shown that FDG PET findings as abnormally increased myocardial uptake correlate well with the cardiac MR biomarkers. FDG PET findings may add complementary and incremental values to cardiac MR by improving the sensitivity of cardiac MR for mild or borderline myocarditis, and increasing specificity for chronic myocarditis. Preliminary data from retrospective and case-based observational studies have suggested the complementary and incremental values of simultaneous cardiac FDG PET/MR for evaluation of myocarditis, compared to PET/CT or MR alone. Well-designed studies are needed to confirm the findings and to assess the value of cardiac PET/MR for clinical management and more importantly patient's outcome in both acute and chronic myocarditis.

Indexed as

Fluorodeoxyglucose F18HumansMagnetic Resonance ImagingMyocarditisPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsCardiacFDGInflammationMRMyocarditisPET/CTPET/MR

Identifiers

PMID31243587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.