Evidence map›Paper›PMID 31243574›Full record

Trial reportLangenbeck's archives of surgery2019

Impact of drains on nausea and vomiting after thyroid and parathyroid surgery: a randomized controlled trial.

B M Künzli, M Walensi, J Wilimsky, C Bucher, T Bührer, C Kull, A Zuse, C A Maurer

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Langenbeck's archives of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01679418 (Randomized Controlled Trial on the Impact of Postoperative Drainage on Nausea and Vomiting After Thyroid- and Parathyroid Surgery), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01679418 nacompletednot on this map

Randomized Controlled Trial on the Impact of Postoperative Drainage on Nausea and Vomiting After Thyroid- and Parathyroid Surgery

TypeinterventionalSponsorKantonsspital LiestalRan2007 to 2012Enrolled139ConditionsPostoperative Nausea and VomitingArmsPlacement of a wound drain post surgery (Redon, Medicoplast), No-drain after surgery
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

B M KünzliDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
M WalensiDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
J WilimskyDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
C BucherDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
T BührerDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
C KullDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland.
A ZuseDepartment of Surgery, HIRSLANDEN Private Hospital Group, Klinik Beau-Site, Schänzlihalde 1, CH - 3013, Bern, Switzerland.
C A MaurerDepartment of Surgery, Hospital of Baselland, Affiliated with the University of Basel, Liestal, Switzerland. christoph.maurer@hin.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNausea and vomiting are common side effects following thyroid and parathyroid surgery. In a prospective controlled randomized trial, postoperative nausea and vomiting (PONV) and the number of episodes of vomiting were defined as two primary endpoints. We analysed whether the placement of drains after thyroid or parathyroid surgery enhances PONV and/or influences vomiting. PATIENTS AND

methodsFrom November 2007 to January 2012, 136 consecutive patients were included for thyroid or parathyroid surgery and were randomly assigned to group A (drain, n = 69) or group B (no drain, n = 67). PONV was assessed with visual analogue scale (VAS; range 0 to 10) measurements. Furthermore, episodes of vomiting as well as analgetic and antiemetic therapies were recorded. Difference in neck circumference was compared pre- and postoperatively.

resultsPatients' characteristics did not differ between group A and B. Postoperative VAS values for pain were 2.4 ± 0.3 (group A) and 2.6 ± 0.2 (group B) (p = 0.62), and for nausea 1.4 ± 0.2 (group A) and 1.1 ± 0.2 (group B) (p = 0.57). The relative occurrences of episodes for postoperative vomiting were equal in both groups 0.3 ± 0.1 (p = 1.0). Antiemetic drugs were administered 37 times (group A) and 18 times (group B) (p = 0.099). The total number of treatments of patients with antiemetic drugs was 23 (33.3%) in group A vs. 13 (19.4%) in group B (p = 0.081). The neck circumference postoperatively was significantly larger in group B (p = 0.0025).

conclusionsDrains after surgery do not enhance postoperative pain, nausea and vomiting. The placement of drains in thyroid surgery is recommended to avoid relevant fluid collection. Drains however may influence the amount of antiemetic drug requirements.

trial registrationCLINICALTRIALS. GOV IDENTIFIER: NCT01679418.

Indexed as

ParathyroidectomyThyroidectomyAdultAgedAged, 80 and overAnalgesicsAntiemeticsDrainageFemaleHumansMaleMiddle AgedPain MeasurementPostoperative Nausea and VomitingPostoperative PainProspective StudiesAnalgesicsAntiemeticsDrainageNauseaPONVSurgeryThyroidThyroidectomyVomiting

Identifiers

PMID31243574

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.