Evidence map›Paper›PMID 31243460›Full record

SynthesisSingapore medical journal2019

A systematic review of the association of obesity with the outcomes of inflammatory rheumatic diseases.

Yi Xuan Lee, Yu Heng Kwan, Ka Keat Lim, Chuen Seng Tan, Nai Lee Lui, Jie Kie Phang, Eng Hui Chew, Truls Ostbye, Julian Thumboo, Warren Fong

Abstract readSystematic Review
In one paragraph

Synthesis in Singapore medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yi Xuan Lee *Department of Pharmacy, National University of Singapore, Singapore.
Yu Heng Kwan *Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Ka Keat LimProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Chuen Seng TanSaw Swee Hock School of Public Health, National University of Singapore, Singapore.
Nai Lee LuiDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore.
Jie Kie PhangDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore.
Eng Hui ChewDepartment of Pharmacy, National University of Singapore, Singapore.
Truls OstbyeProgramme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
Julian ThumbooDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore.
Warren FongDepartment of Rheumatology and Immunology, Singapore General Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This was a systematic review of the literature on the association between obesity and the outcome of inflammatory rheumatic diseases. We conducted a literature search using PubMed®, Embase and PsycINFO®. Articles were classified into three categories based on the effects of obesity on the outcomes of inflammatory rheumatic diseases. The subject population, country, type of studies, number of patients, measurement of obesity and outcomes assessed were presented. Quality was appraised using Kmet et al's criteria. 4,331 articles were screened and 60 were relevant to the objective. Obesity had a negative, positive and neutral association with outcomes of inflammatory rheumatic diseases in 38 (63.3%) studies with 57,612 subjects, 11 (18.3%) studies with 3,866 subjects, and 11 (18.3%) studies with 3,834 subjects, respectively. In most studies, the disease population had been diagnosed with rheumatoid arthritis (RA). Tumour necrosis factor-α inhibitors were mostly associated with negative outcomes. More studies examining subjects outside Europe and North America and diseases other than RA are warranted.

Indexed as

Arthritis, RheumatoidHumansObesityRheumatic DiseasesTreatment Outcomeassociationobesityoutcomesrheumatology

Identifiers

PMID31243460
PMCPMC6595055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.