Evidence map›Paper›PMID 31243296›Full record

ArticleScientific reports2019

Adult Pgf

Vanessa R Kay, Lindsay S Cahill, Anas Hanif, John G Sled, Peter Carmeliet, Chandrakant Tayade, B Anne Croy

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Vanessa R KayDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada. 8vrk@queensu.ca.ORCID http://orcid.org/0000-0002-8685-2348
Lindsay S CahillMouse Imaging Centre, Hospital for Sick Children, Toronto, ON, M5T 3H7, Canada.
Anas HanifDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
John G SledMouse Imaging Centre, Hospital for Sick Children, Toronto, ON, M5T 3H7, Canada.
Peter CarmelietLaboratory of Angiogenesis and Vascular Metabolism, VIB - Vesalius Research Center, University of Leuven, Department of Oncology, Leuven, Belgium.
Chandrakant TayadeDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
B Anne CroyDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, K7L 3N6, Canada.
Queen's University · CAHospital for Sick Children · CAKU Leuven · BEUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Offspring of preeclamptic pregnancies have cognitive alterations. Placental growth factor (PGF), is low in preeclampsia; reduced levels may affect brain development. PGF-null mice differ from normal congenic controls in cerebrovasculature, neuroanatomy and behavior. Using brain imaging and behavioral testing, we asked whether developmentally asynchronous (i.e. neonatal) PGF supplementation alters the vascular, neuroanatomic and/or behavioral status of Pgf

Indexed as

Behavior, AnimalAnimalsAnimals, NewbornAnxietyBody WeightBrainCerebrumContrast MediaDepressionFemaleGadoliniumMagnetic Resonance ImagingMaleMaze LearningMiceMice, Inbred C57BLContrast MediaGadoliniumPgf protein, mousePlacenta Growth FactorRecombinant ProteinsVascular Endothelial Growth Factor A

Identifiers

PMID31243296
PMCPMC6594955
OpenAlexW2954293648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.