Evidence map›Paper›PMID 31243050›Full record

ArticleJournal of cell science2019

Microtubule glycylation promotes attachment of basal bodies to the cell cortex.

Anthony D Junker, Adam W J Soh, Eileen T O'Toole, Janet B Meehl, Mayukh Guha, Mark Winey, Jerry E Honts, Jacek Gaertig, Chad G Pearson

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Post-Translational Modifications in Cilia and Ciliopathies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Basal bodies bend in response to ciliary forces.Molecular biology of the cell · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Posttranslational modifications of the cytoskeleton.Cytoskeleton (Hoboken, N.J.) · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Motile Cilia: Innovation and Insight From Ciliate Model Organisms.Frontiers in cell and developmental biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Anthony D JunkerDepartment of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Adam W J SohDepartment of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Eileen T O'TooleDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80302, USA.
Janet B MeehlDepartment of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80302, USA.
Mayukh GuhaDepartment of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
Mark WineyDepartment of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA.
Jerry E HontsDepartment of Biology, Drake University, 2507 University Avenue, Des Moines, IA 50311, USA.
Jacek GaertigDepartment of Cellular Biology, University of Georgia, Athens, GA 30602, USA.
Chad G PearsonDepartment of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA Chad.Pearson@ucdenver.edu.ORCID 0000-0003-1915-6593
University of Colorado Denver · USUniversity of Colorado Boulder · USUniversity of Georgia · USDrake University · USUniversity of California, Davis · US

Funding

Mechanisms of centriole assembly and stabilityR01GM099820 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI PEARSON, CHAD G · 2012 to 2020
$2.9M
MIPS (Microtubule Inner Proteins) function in cilia and basal bodiesR01GM127571 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WINEY, MARK · 2018 to 2025
$2.5M
Regulation of Cilium LengthR21HD092809 · NICHD · UNIVERSITY OF GEORGIA · PI GAERTIG, JACEK · 2017 to 2018
$413k
Basal body post-translational modifications promote resistance to ciliary forceF31HL147495 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI JUNKER, ANTHONY · 2019 to 2020
$67k
NHLBI NIH HHS F31 HL147495NICHD NIH HHS R21 HD092809NIGMS NIH HHS R01 GM099820NIGMS NIH HHS R01 GM127571
6 · The paper itself

Abstract

Motile cilia generate directed hydrodynamic flow that is important for the motility of cells and extracellular fluids. To optimize directed hydrodynamic flow, motile cilia are organized and oriented into a polarized array. Basal bodies (BBs) nucleate and position motile cilia at the cell cortex. Cytoplasmic BB-associated microtubules are conserved structures that extend from BBs. By using the ciliate,

Indexed as

Basal BodiesCiliaGlycosylationMicrotubulesMutationTetrahymena thermophilaBasal bodiesCiliaCiliary arrayMicrotubuleMulticiliated cellsTubulin post-translational modifications

Identifiers

PMID31243050
PMCPMC6703707
OpenAlexW2954880740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.