Evidence map›Paper›PMID 31243008›Full record

ArticleArchives of disease in childhood2020

Origins of disparities in preventable child mortality in England and Sweden: a birth cohort study.

Ania Zylbersztejn, Ruth Gilbert, Anders Hjern, Pia Hardelid

Open access · hybridAbstract read
In one paragraph

Article in Archives of disease in childhood, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ania ZylbersztejnPopulation, Policy and Practice, University College London Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0003-1035-1448
Ruth GilbertPopulation, Policy and Practice, University College London Great Ormond Street Institute of Child Health, London, UK.
Anders HjernCentre for Health Equity Studies (CHESS), Stockholm University, Stockholm, Sweden.
Pia HardelidPopulation, Policy and Practice, University College London Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0002-0154-1306
Great Ormond Street Hospital · GBStockholm University · SE

Funding

Arthritis Research UKBritish Heart FoundationCancer Research UKChief Scientist Office [UK]Department of Health 05/40/04Department of Health RP-PG-0407-10314Medical Research Council MC_PC_13041Medical Research Council MR/K006584/1Wellcome Trust
6 · The paper itself

Abstract

objectiveTo compare mortality in children aged <5 years from two causes amenable to healthcare prevention in England and Sweden: respiratory tract infection (RTI) and sudden unexpected death in infancy (SUDI).

designBirth cohort study using linked administrative health databases from England and Sweden. SETTING AND

participantsSingleton live births between 2003 and 2012 in England and Sweden, followed up from age 31 days until the fifth birthday, death or 31 December 2013.

main outcome measuresThe main outcome measures were HR for RTI-related mortality at 31-364 days and at 1-4 years and SUDI mortality at 31-364 days in England versus Sweden estimated using Cox proportional hazards models. We calculated unadjusted HRs and HRs adjusted for birth characteristics (gestational age, birth weight, sex and congenital anomalies) and socioeconomic factors (maternal age and socioeconomic status).

resultsThe English cohort comprised 3 928 483 births, 768 RTI-related deaths at 31-364 days, 691 RTI-related deaths at 1-4 years and 1166 SUDIs; the corresponding figures for the Swedish cohort were 1 012 682, 131, 118 and 189. At 31-364 days, unadjusted HR for RTI-related death in England versus Sweden was 1.52 (95% CI 1.26 to 1.82). After adjusting for birth characteristics, the HR reduced to 1.16 (95% CI 0.96 to 1.40) and for socioeconomic factors to 1.11 (95% CI 0.92 to 1.34). At 1-4 years, unadjusted HR was 1.58 (95% CI 1.30 to 1.92) and decreased to 1.32 (95% CI 1.09 to 1.61) after adjusting for birth characteristics and to 1.30 (95% CI 1.07 to 1.59) after further adjustment for socioeconomic factors. For SUDI, the respective HRs were 1.59 (95% CI 1.36 to 1.85) in the unadjusted model, and 1.40 (95% CI 1.20 to 1.63) after accounting for birth characteristics and 1.19 (95% CI 1.02 to 1.39) in the fully adjusted model.

conclusionInterventions that improve maternal health before and during pregnancy to reduce the prevalence of adverse birth characteristics and address poverty could reduce child mortality due to RTIs and SUDIs in England.

Indexed as

Child MortalityCause of DeathChild, PreschoolCohort StudiesFemaleHealthcare DisparitiesHumansInfantInfant MortalityInfant, NewbornMaleRisk FactorsSwedenUnited Kingdomchild mortalityEnglandrespiratory tract Infectionsudden unexpected death In infancySweden

Identifiers

PMID31243008
PMCPMC6951233
OpenAlexW2955951513

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.