ArticleBMC psychiatry2019
Implications of the clinical gestational diagnosis of ZIKV infection in the manifestation of symptoms of postpartum depression: a case-control study.
Article in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04595123 (Impact of COVID-19 Pandemic in Perinatal Mental Health), which is not on this map. Cited by 4 papers.
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Impact of COVID-19 Pandemic in Perinatal Mental Health
Who cites it
4 citing papers in PubMed.
- Zika Virus Inoculation During Pregnancy Impaired Maternal Care and Altered Prolactin and Corticosterone Levels in Rats.Developmental neurobiology · 2026Article
- Non-biological factors associated with postpartum depression among women in Shenzhen: a case-control study.Frontiers in public health · 2024Article
- Analysis of influencing factors and the construction of predictive models for postpartum depression in older pregnant women.World journal of psychiatry · 2023Article
- Risk factors for the development of postpartum depression in individuals who screened positive for antenatal depression.BMC psychiatry · 2023Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraumatic events can trigger postpartum depression. Pregnant women in Brazil today are facing an extremely stressful experience. Thus, the objective here was to analyze the prevalence of symptoms of depression in the immediate postpartum period (IPPD) and associate these symptoms with previous stressful, social, psychological, behavioral, obstetrical, clinical, violent and infectious events, particularly exposure to Zika virus (ZIKV) infection during pregnancy.
methodsThis was a case-control study. The sample comprised 213 puerperal women treated in the maternity ward of a public reference hospital in the Araguaia River Valley of Mato Grosso and Goiás, Brazil. Severe IPPD symptoms were confirmed based on the Edinburgh Postnatal Depression Scale (EPDS). A descriptive statistical analysis was carried out using the Epi Info™ version 7.1.5 suite of software tools and the Statistical Package for Social Sciences (SPSS) version 21.0.
resultsA bivariate analysis revealed a significant association between "severe symptoms of IPPD" and the following variables: "clinical diagnosis of ZIKV during pregnancy" (OR = 13.36; 95% CI = 5.34-33.39); "was separated or divorced in the last year" (OR = 3.58; 95% CI = 1.42-8.99); "suffered an accident in the last year" (OR = 3.32, 95% CI = 1.12-9.82); "suffered emotional violence during pregnancy" (OR = 3.80; 95% CI = 1.81-7.99); "suffered physical violence during pregnancy" (OR = 11.86; 95% CI = 2.07-67.82); "fear of her partner" (OR = 17.90; 95% CI = 3.44-92.99); "dengue fever during pregnancy" (OR = 7.85; 95% CI: 1.66-37.05), and "has a family member diagnosed with mental illness" (OR = 2.54; 95% CI = 1.09-5.93). The multivariate analysis confirmed the association of severe PPD symptoms only with the variables of "clinical diagnosis of ZIKV during pregnancy" (OR = 19.82; 95% CI: 5.35-73.39) and "was separated or divorced in the last year" (OR = 3.92; 95% IC = 1.12-13.63).
conclusionsClinically diagnosed ZIKV during pregnancy may be one of the main events associated with severe IPPD symptoms, showing an almost 20-fold higher chance of occurrence than other factors.
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