Evidence map›Paper›PMID 31242834›Full record

ReviewCurrent pediatric reviews2019

Definition of Opportunistic Infections in Immunocompromised Children on the Basis of Etiologies and Clinical Features: A Summary for Practical Purposes.

Niccolò Riccardi, Gioacchino Andrea Rotulo, Elio Castagnola

Open access · hybridAbstract readReview
In one paragraph

Review in Current pediatric reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Prevalence of Enterocytozoon bieneusi and Encephalitozoon spp. in Swedish patients with suspected gastrointestinal parasite infection: a cross-sectional molecular study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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  9. Antimicrobial Investigation of Phthalimide andLife (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Niccolò RiccardiInfectious Diseases Clinic, Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Gioacchino Andrea RotuloInfectious Diseases Department, Istituto Giannina Gaslini Children's Hospital, University of Genoa, Geno, Italy.
Elio CastagnolaInfectious Diseases Department, Istituto Giannina Gaslini, Children's Hospital, Genoa, Italy.
Istituto Giannina Gaslini · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Opportunistic Infections (OIs) still remain a major cause of morbidity and death in children with either malignant or nonmalignant disease. OIs are defined as those infections occurring due to bacteria, fungi, viruses or commensal organisms that normally inhabit the human body and do not cause a disease in healthy people, but become pathogenic when the body's defense system is impaired. OIs can also be represented by unusually severe infections caused by common pathogens. An OI could present itself at the onset of a primary immunodeficiency syndrome as a life-threatening event. More often, OI is a therapyassociated complication in patients needing immunosuppressive treatment, among long-term hospitalised patients or in children who undergo bone marrow or solid organ transplantation. The aim of the present review is to provide a comprehensive and 'easy to read' text that briefly summarises the currently available knowledge about OIs in order to define when an infection should be considered as opportunistic in pediatrics as a result of an underlying congenital or acquired immune-deficit.

Indexed as

Bacterial InfectionsChildChronic DiseaseClinical Trials as TopicGuidelines as TopicHumansImmunocompromised HostImmunologic Deficiency SyndromesImmunosuppressive AgentsMycosesOpportunistic InfectionsVirus DiseasesImmunosuppressive Agentschildrenetiologyimmune-deficitimmunocompromised hostmalignantOpportunistic infectionspathogenic.

Identifiers

PMID31242834
PMCPMC7040525
OpenAlexW2953169373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.