Evidence map›Paper›PMID 31242809›Full record

ArticleCell cycle (Georgetown, Tex.)2019

Tissue stem cells: the new actors in the aneuploidy field.

Rita Brás, Claudio E Sunkel, Luís Pedro Resende

Abstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rita Brása Instituto de Investigação e Inovação em Saúde, Universidade do Porto , Porto , Portugal.ORCID 0000-0002-7136-6865
Claudio E Sunkela Instituto de Investigação e Inovação em Saúde, Universidade do Porto , Porto , Portugal.
Luís Pedro Resendea Instituto de Investigação e Inovação em Saúde, Universidade do Porto , Porto , Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of multicellular organisms and the maintenance of its tissues relies on mitosis. However, this process represents a major challenge for genomic stability as each time a cell division occurs there are multiple steps where errors can lead to an abnormal chromosomal content in daughter cells - aneuploidy. Aneuploidy was first postulated to act as a tumour promoting agent over one century ago. Since then, we have learned to appreciate the complexity involving the cellular responses to aneuploidy and to value the importance of models where aneuploidy is induced

Indexed as

AneuploidyAnimalsCell ProliferationCell SurvivalCell Transformation, NeoplasticChromosomal InstabilityDrosophilaHumansMitosisStem CellsaneuploidycancermitosisStem cells

Identifiers

PMID31242809
PMCPMC6681780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.