Evidence map›Paper›PMID 31242638›Full record

ReviewNutrients2019

Potential Factors Influencing the Effects of Anthocyanins on Blood Pressure Regulation in Humans: A Review.

Stefano Vendrame, Dorothy Klimis-Zacas

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 7 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 7 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Roselle for hypertension in adults.The Cochrane database of systematic reviews · 2021
    Pooled it
  7. Roselle for hypertension in adults.The Cochrane database of systematic reviews · 2010
    Pooled it
  8. Trial
  9. The influence of tart cherries (Journal of nutritional science · 2021
    Trial
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Impact of cyanidin 3-Journal of clinical biochemistry and nutrition · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Chokeberry (Nutrients · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stefano VendrameSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA. stefano.vendrame@fulbrightmail.org.
Dorothy Klimis-ZacasSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA. dorothea@maine.edu.
University of Maine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary intake of anthocyanins (ACNs) is associated with a reduced risk of cardiovascular and coronary heart disease. While the anti-inflammatory, antioxidant, and lipid-lowering effects of ACN consumption have been consistently reported, their effect(s) on blood pressure regulation is less consistent and results from human studies are mixed. The objective of this review is attempting to identify potential patterns which may explain the variability in results related to blood pressure. To do so, we review 66 human intervention trials testing the effects on blood pressure of purified ACN or ACN-rich extracts, or whole berries, berry juices, powders, purees and whole phenolic extracts, from berries that are rich in ACN and have ACNs as predominant bioactives. Several factors appear to be involved on the mixed results reported. In particular, the baseline characteristics of the population in terms of blood pressure and total flavonoid intake, the dose and duration of the intervention, the differential effects of individual ACN and their synergistic effects with other phytochemicals, the ACN content and bioavailability from the food matrix, and individual differences in ACN absorption and metabolism related to genotype and microbiota enterotypes.

Indexed as

Diet, HealthyAdolescentAdultAnthocyaninsAntihypertensive AgentsBlood PressureFemaleHumansHypertensionMaleMiddle AgedPlant PreparationsTreatment OutcomeYoung AdultAnthocyaninsAntihypertensive AgentsPlant Preparationsanthocyaninsberriesblood pressurehypertension

Identifiers

PMID31242638
PMCPMC6628116
OpenAlexW2955630689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.