Evidence map›Paper›PMID 31242632›Full record

ReviewVaccines2019

Subunit Vaccine Approaches for African Swine Fever Virus.

Natasha N Gaudreault, Juergen A Richt

Abstract readReview
In one paragraph

Review in Vaccines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 109 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
109citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

109 citing papers in PubMed, 1 synthesis or guideline pooled it.

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49 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natasha N GaudreaultDepartment of Diagnostic Medicine & Pathobiology, College of Veterinary Medicine, Kansas State University, K224 Mosier Hall, 1800 Denison Ave, Manhattan, KS 66506, USA. nng5757@vet.k-state.edu.
Juergen A RichtDepartment of Diagnostic Medicine & Pathobiology, College of Veterinary Medicine, Kansas State University, K224 Mosier Hall, 1800 Denison Ave, Manhattan, KS 66506, USA. jricht@vet.k-state.edu.

Funding

State of Kansas National Bio and Agro-Defense Facility transition funds NAU.S. Department of Homeland Security DHS-2010-ST-061-AG0001
6 · The paper itself

Abstract

African swine fever virus (ASFV) is the cause of a highly fatal disease in swine, for which there is no available vaccine. The disease is highly contagious and poses a serious threat to the swine industry worldwide. Since its introduction to the Caucasus region in 2007, a highly virulent, genotype II strain of ASFV has continued to circulate and spread into Eastern Europe and Russia, and most recently into Western Europe, China, and various countries of Southeast Asia. This review summarizes various ASFV vaccine strategies that have been investigated, with focus on antigen-, DNA-, and virus vector-based vaccines. Known ASFV antigens and the determinants of protection against ASFV versus immunopathological enhancement of infection and disease are also discussed.

Indexed as

African swine fever virusantibody dependent enhancementantigensASFVdisease enhancementimmunogensprotective immunitysubunit vaccinesvaccines

Identifiers

PMID31242632
PMCPMC6631172

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.