Evidence map›Paper›PMID 31242602›Full record

ReviewNutrients2019

In Search of Panacea-Review of Recent Studies Concerning Nature-Derived Anticancer Agents.

Dawid Przystupski, Magdalena J Niemczura, Agata Górska, Stanisław Supplitt, Krzysztof Kotowski, Piotr Wawryka, Paulina Rozborska, Kinga Woźniak, Olga Michel, Aleksander Kiełbik and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Frontiers in microbiology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Novel assay to measure chromosome instability identifiesFrontiers in bioengineering and biotechnology · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dawid PrzystupskiFaculty of Medicine, Wroclaw Medical University, J. Mikulicza-Radeckiego 5, 50-345 Wroclaw, Poland. dawid.przystupski@gmail.com.ORCID 0000-0003-1706-3297
Magdalena J NiemczuraDepartment of Biological Sciences, Institute of Experimental Biology, University of Wrocław, Kanonia 6/8, 50-328 Wroclaw, Poland. m.j.niemczura@gmail.com.
Agata GórskaDepartment of Biological Sciences, Institute of Experimental Biology, University of Wrocław, Kanonia 6/8, 50-328 Wroclaw, Poland. agata_gorska@onet.eu.
Stanisław SupplittFaculty of Medicine, Wroclaw Medical University, J. Mikulicza-Radeckiego 5, 50-345 Wroclaw, Poland. stkwiatek@gmail.com.
Krzysztof KotowskiFaculty of Medicine, Wroclaw Medical University, J. Mikulicza-Radeckiego 5, 50-345 Wroclaw, Poland. krzysztof.kotowski96@gmail.com.
Piotr WawrykaFaculty of Medicine, Wroclaw Medical University, J. Mikulicza-Radeckiego 5, 50-345 Wroclaw, Poland. piotr95wawryka@gmail.com.
Paulina RozborskaFaculty of Chemistry, Wroclaw University of Science and Technology, Norwida 4/6, 50-373 Wroclaw, Poland. rozborska.paulina@gmail.com.
Kinga WoźniakFaculty of Chemistry, Wroclaw University of Science and Technology, Norwida 4/6, 50-373 Wroclaw, Poland. kinga.wozniak@onet.eu.
Olga MichelDepartment of Medical Biochemistry, Wroclaw Medical University, Chalubinskiego 10, 50-368 13 Wroclaw, Poland. michel.olga.maria@gmail.com.
Aleksander KiełbikFaculty of Medicine, Wroclaw Medical University, J. Mikulicza-Radeckiego 5, 50-345 Wroclaw, Poland. akielbik6@gmail.com.
Weronika BartosikFaculty of Biotechnology, University of Wroclaw, Joliot-Curie 14a, 50-385 Wroclaw, Poland. weronikabartosik@gmail.com.
Jolanta SaczkoDepartment of Molecular and Cellular Biology, Wroclaw Medical University, Borowska 211A, 50-25 556 Wroclaw, Poland. jolanta.saczko@umed.wroc.pl.
Julita KulbackaDepartment of Molecular and Cellular Biology, Wroclaw Medical University, Borowska 211A, 50-25 556 Wroclaw, Poland. julita.kulbacka@umed.wroc.pl.ORCID 0000-0001-8272-5440
Wroclaw Medical University · PLUniversity of Wrocław · PLWrocław University of Science and Technology · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego "Najlepsi z Najlepszych 3.0" PO WER (2014-2020) (POWR.Z600.18.002.)Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu Statutory Funds of Department of Molecular and Cellular Biology
6 · The paper itself

Abstract

Cancers are one of the leading causes of deaths affecting millions of people around the world, therefore they are currently a major public health problem. The treatment of cancer is based on surgical resection, radiotherapy, chemotherapy or immunotherapy, much of which is often insufficient and cause serious, burdensome and undesirable side effects. For many years, assorted secondary metabolites derived from plants have been used as antitumor agents. Recently, researchers have discovered a large number of new natural substances which can effectively interfere with cancer cells' metabolism. The most famous groups of these compounds are topoisomerase and mitotic inhibitors. The aim of the latest research is to characterize natural compounds found in many common foods, especially by means of their abilities to regulate cell cycle, growth and differentiation, as well as epigenetic modulation. In this paper, we focus on a review of recent discoveries regarding nature-derived anticancer agents.

Indexed as

DietAnimalsAntimitotic AgentsAntineoplastic Agents, PhytogenicCell CycleCell DifferentiationCell ProliferationDrug Resistance, NeoplasmEnergy MetabolismEpigenesis, GeneticHumansNeoplasmsTopoisomerase InhibitorsAntimitotic AgentsAntineoplastic Agents, PhytogenicTopoisomerase Inhibitors6-gingerolanticancer researchchemopreventiondrug resistancehonokiolmitotic inhibitorsnatural substancesnutraceuticalsnutri-epigeneticsphytochemicalspolyphenolstopoisomerase inhibitorsxenobiotics

Identifiers

PMID31242602
PMCPMC6627480
OpenAlexW2953416229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.