Evidence map›Paper›PMID 31242573›Full record

ArticleMolecules (Basel, Switzerland)2019

Development of a Method for the Quantification of Clotrimazole and Itraconazole and Study of Their Stability in a New Microemulsion for the Treatment of Sporotrichosis.

Patricia Garcia Ferreira, Carolina Guimarães de Souza Lima, Letícia Lorena Noronha, Marcela Cristina de Moraes, Fernando de Carvalho da Silva, Alessandra Lifsitch Viçosa, Débora Omena Futuro, Vitor Francisco Ferreira

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Co-amorphization for solubility and dissolution rate improvement: the case of low-crystallization-tendency drugs.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Patricia Garcia FerreiraDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Niterói-RJ 24241-000, Brazil. patricia.pharma@yahoo.com.br.
Carolina Guimarães de Souza LimaDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói-RJ 24210-141, Brazil. carolgslima@gmail.com.
Letícia Lorena NoronhaDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Niterói-RJ 24241-000, Brazil. leticianoronha95@gmail.com.
Marcela Cristina de MoraesDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói-RJ 24210-141, Brazil. mcmoraes@id.uff.br.
Fernando de Carvalho da SilvaDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói-RJ 24210-141, Brazil. gqofernando@vm.uff.br.ORCID 0000-0002-2042-3778
Alessandra Lifsitch ViçosaFundação Oswaldo Cruz (FIOCRUZ), Farmanguinhos-Manguinhos, Avenida Sinzenando Nabuco 100, Rio de Janeiro-RJ 21045-900, Brazil. alessandra.vicosa@far.fiocruz.br.ORCID 0000-0001-8511-0003
Débora Omena FuturoDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Niterói-RJ 24241-000, Brazil. dfuturo@id.uff.br.
Vitor Francisco FerreiraDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Niterói-RJ 24241-000, Brazil. vitorferreira@id.uff.br.
Universidade Federal Fluminense · BRFundação Oswaldo Cruz · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 303713/2014-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/2002.800/2017Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/200.930/2017
6 · The paper itself

Abstract

Sporotrichosis occurs worldwide and is caused by the fungus

Indexed as

Drug CompoundingAntifungal AgentsCalorimetry, Differential ScanningClotrimazoleDrug InteractionsDrug StabilityEmulsionsItraconazoleMolecular StructureSensitivity and SpecificitySporotrichosisStructure-Activity RelationshipThermogravimetryAntifungal AgentsClotrimazoleEmulsionsItraconazoleclotrimazoleitraconazolemethod validationpre-development processsporotrichosisstability

Identifiers

PMID31242573
PMCPMC6630458
OpenAlexW2954750188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.